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Documenting Pharmacogenomic Test Results in Electronic Health Records: Practical Considerations for Primary Care Teams

With increasing patient interest in and access to pharmacogenomic testing, clinicians practicing in primary care are more likely than ever to encounter a patient seeking or presenting with pharmacogenomic test results. Gene-based prescribing recommendations are available to healthcare providers thro...

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Detalles Bibliográficos
Autores principales: Gammal, Roseann S., Berenbrok, Lucas A., Empey, Philip E., Massart, Mylynda B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706275/
https://www.ncbi.nlm.nih.gov/pubmed/34945768
http://dx.doi.org/10.3390/jpm11121296
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author Gammal, Roseann S.
Berenbrok, Lucas A.
Empey, Philip E.
Massart, Mylynda B.
author_facet Gammal, Roseann S.
Berenbrok, Lucas A.
Empey, Philip E.
Massart, Mylynda B.
author_sort Gammal, Roseann S.
collection PubMed
description With increasing patient interest in and access to pharmacogenomic testing, clinicians practicing in primary care are more likely than ever to encounter a patient seeking or presenting with pharmacogenomic test results. Gene-based prescribing recommendations are available to healthcare providers through Food and Drug Administration-approved drug labeling and Clinical Pharmacogenetics Implementation Consortium guidelines. Given the lifelong utility of pharmacogenomic test results to optimize pharmacotherapy for commonly prescribed medications, appropriate documentation of these results in a patient’s electronic health record (EHR) is essential. The current “gold standard” for pharmacogenomics implementation includes entering pharmacogenomic test results into EHRs as discrete results with associated clinical decision support (CDS) alerts that will fire at the point of prescribing, similar to drug allergy alerts. However, such infrastructure is limited to the few institutions that have invested in the resources and personnel to develop and maintain it. For the majority of clinicians who do not practice at an institution with a dedicated clinical pharmacogenomics team and integrated pharmacogenomics CDS in the EHR, this report provides practical tips for documenting pharmacogenomic test results in the problem list and allergy field to maximize the visibility and utility of results over time, especially when such results could prevent the occurrence of serious adverse drug reactions or predict therapeutic failure.
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spelling pubmed-87062752021-12-25 Documenting Pharmacogenomic Test Results in Electronic Health Records: Practical Considerations for Primary Care Teams Gammal, Roseann S. Berenbrok, Lucas A. Empey, Philip E. Massart, Mylynda B. J Pers Med Commentary With increasing patient interest in and access to pharmacogenomic testing, clinicians practicing in primary care are more likely than ever to encounter a patient seeking or presenting with pharmacogenomic test results. Gene-based prescribing recommendations are available to healthcare providers through Food and Drug Administration-approved drug labeling and Clinical Pharmacogenetics Implementation Consortium guidelines. Given the lifelong utility of pharmacogenomic test results to optimize pharmacotherapy for commonly prescribed medications, appropriate documentation of these results in a patient’s electronic health record (EHR) is essential. The current “gold standard” for pharmacogenomics implementation includes entering pharmacogenomic test results into EHRs as discrete results with associated clinical decision support (CDS) alerts that will fire at the point of prescribing, similar to drug allergy alerts. However, such infrastructure is limited to the few institutions that have invested in the resources and personnel to develop and maintain it. For the majority of clinicians who do not practice at an institution with a dedicated clinical pharmacogenomics team and integrated pharmacogenomics CDS in the EHR, this report provides practical tips for documenting pharmacogenomic test results in the problem list and allergy field to maximize the visibility and utility of results over time, especially when such results could prevent the occurrence of serious adverse drug reactions or predict therapeutic failure. MDPI 2021-12-04 /pmc/articles/PMC8706275/ /pubmed/34945768 http://dx.doi.org/10.3390/jpm11121296 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Commentary
Gammal, Roseann S.
Berenbrok, Lucas A.
Empey, Philip E.
Massart, Mylynda B.
Documenting Pharmacogenomic Test Results in Electronic Health Records: Practical Considerations for Primary Care Teams
title Documenting Pharmacogenomic Test Results in Electronic Health Records: Practical Considerations for Primary Care Teams
title_full Documenting Pharmacogenomic Test Results in Electronic Health Records: Practical Considerations for Primary Care Teams
title_fullStr Documenting Pharmacogenomic Test Results in Electronic Health Records: Practical Considerations for Primary Care Teams
title_full_unstemmed Documenting Pharmacogenomic Test Results in Electronic Health Records: Practical Considerations for Primary Care Teams
title_short Documenting Pharmacogenomic Test Results in Electronic Health Records: Practical Considerations for Primary Care Teams
title_sort documenting pharmacogenomic test results in electronic health records: practical considerations for primary care teams
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706275/
https://www.ncbi.nlm.nih.gov/pubmed/34945768
http://dx.doi.org/10.3390/jpm11121296
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