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Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma: An Update on Heterogeneity and Therapeutic Targeting

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related morbidity and mortality in the western world, with limited therapeutic strategies and dismal long-term survival. Cancer-associated fibroblasts (CAFs) are key components of the pancreatic tumor microenvironment, maintaining...

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Detalles Bibliográficos
Autores principales: Vaish, Utpreksha, Jain, Tejeshwar, Are, Abhi C., Dudeja, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706283/
https://www.ncbi.nlm.nih.gov/pubmed/34948209
http://dx.doi.org/10.3390/ijms222413408