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K(Ca)1.1 K(+) Channel Inhibition Overcomes Resistance to Antiandrogens and Doxorubicin in a Human Prostate Cancer LNCaP Spheroid Model

Several types of K(+) channels play crucial roles in tumorigenicity, stemness, invasiveness, and drug resistance in cancer. Spheroid formation of human prostate cancer (PC) LNCaP cells with ultra-low attachment surface cultureware induced the up-regulation of cancer stem cell markers, such as NANOG,...

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Detalles Bibliográficos
Autores principales:	Ohya, Susumu, Kajikuri, Junko, Endo, Kyoko, Kito, Hiroaki, Matsui, Miki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706449/ https://www.ncbi.nlm.nih.gov/pubmed/34948357 http://dx.doi.org/10.3390/ijms222413553

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