Cyclosporine-induced Leukoencephalopathy Precipitated Following Interaction with Ciprofloxacin

A bone marrow transplant recipient on cyclosporine initiated on ciprofloxacin for a renal abscess presented with encephalopathy, right hemiparesis, and multiorgan dysfunction. Imaging revealed white matter signal changes characteristic of cyclosporine leukoencephalopathy. This case illustrates the p...

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Detalles Bibliográficos
Autores principales: Nagabushana, Divya, Chandrasekhar, Supraja, Ramprakash, Stalin, Avathi Venkatesha, Gurudutt, Helavar, Rajesh V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Neuroimaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706601/
https://www.ncbi.nlm.nih.gov/pubmed/35018187
http://dx.doi.org/10.4103/jpn.JPN_130_20
Descripción
Sumario:A bone marrow transplant recipient on cyclosporine initiated on ciprofloxacin for a renal abscess presented with encephalopathy, right hemiparesis, and multiorgan dysfunction. Imaging revealed white matter signal changes characteristic of cyclosporine leukoencephalopathy. This case illustrates the potential drug interaction of cyclosporine with ciprofloxacin and the need to exercise caution while prescribing antibiotics with cyclosporine.

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