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A Hybrid Model to Predict Formulation Dependent Granule Growth in a Bi-Component Wet Granulation Process

In this study, a hybrid modeling framework was developed for predicting size distribution and content uniformity of granules in a bi-component wet granulation system with components of differing hydrophobicities. Two bi-component formulations, (1) ibuprofen-USP and micro-crystalline cellulose and (2...

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Detalles Bibliográficos
Autores principales:	Muthancheri, Indu, Ramachandran, Rohit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706642/ https://www.ncbi.nlm.nih.gov/pubmed/34959342 http://dx.doi.org/10.3390/pharmaceutics13122063

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