SFRP4 Expression Is Linked to Immune-Driven Fibrotic Conditions, Correlates with Skin and Lung Fibrosis in SSc and a Potential EMT Biomarker

Secreted Frizzled Receptor Protein 4 (SFRP4) has been shown to be increased in Scleroderma (SSc). To determine its role in immune-driven fibrosis, we analysed SSc and sclerotic Chronic Graft Versus Host Disease (sclGVHD) biosamples; skin biopsies (n = 24) from chronic GVHD patients (8 with and 5 wit...

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Detalles Bibliográficos
Autores principales: Tinazzi, Ilaria, Mulipa, Panji, Colato, Chiara, Abignano, Giuseppina, Ballarin, Andrea, Biasi, Domenico, Emery, Paul, Ross, Rebecca L., Del Galdo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706846/
https://www.ncbi.nlm.nih.gov/pubmed/34945116
http://dx.doi.org/10.3390/jcm10245820

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