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Down-Regulation of Yeast Helicase Ded1 by Glucose Starvation or Heat-Shock Differentially Impairs Translation of Ded1-Dependent mRNAs

Ded1 is an essential DEAD-box helicase in yeast that broadly stimulates translation initiation and is critical for mRNAs with structured 5′UTRs. Recent evidence suggests that the condensation of Ded1 in mRNA granules down-regulates Ded1 function during heat-shock and glucose starvation. We examined...

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Detalles Bibliográficos
Autores principales:	Sen, Neelam Dabas, Zhang, Hongen, Hinnebusch, Alan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706886/ https://www.ncbi.nlm.nih.gov/pubmed/34946015 http://dx.doi.org/10.3390/microorganisms9122413

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