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Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK

Vaccination plays a key role in reducing morbidity and mortality caused by infectious diseases, including the recent COVID-19 pandemic. However, a comprehensive approach that allows the planning of vaccination campaigns and the estimation of the resources required to deliver and administer COVID-19...

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Autores principales: Ibrahim, Dauda, Kis, Zoltán, Tak, Kyungjae, Papathanasiou, Maria M., Kontoravdi, Cleo, Chachuat, Benoît, Shah, Nilay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706890/
https://www.ncbi.nlm.nih.gov/pubmed/34960206
http://dx.doi.org/10.3390/vaccines9121460
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author Ibrahim, Dauda
Kis, Zoltán
Tak, Kyungjae
Papathanasiou, Maria M.
Kontoravdi, Cleo
Chachuat, Benoît
Shah, Nilay
author_facet Ibrahim, Dauda
Kis, Zoltán
Tak, Kyungjae
Papathanasiou, Maria M.
Kontoravdi, Cleo
Chachuat, Benoît
Shah, Nilay
author_sort Ibrahim, Dauda
collection PubMed
description Vaccination plays a key role in reducing morbidity and mortality caused by infectious diseases, including the recent COVID-19 pandemic. However, a comprehensive approach that allows the planning of vaccination campaigns and the estimation of the resources required to deliver and administer COVID-19 vaccines is lacking. This work implements a new framework that supports the planning and delivery of vaccination campaigns. Firstly, the framework segments and priorities target populations, then estimates vaccination timeframe and workforce requirements, and lastly predicts logistics costs and facilitates the distribution of vaccines from manufacturing plants to vaccination centres. The outcomes from this study reveal the necessary resources required and their associated costs ahead of a vaccination campaign. Analysis of results shows that by integrating demand stratification, administration, and the supply chain, the synergy amongst these activities can be exploited to allow planning and cost-effective delivery of a vaccination campaign against COVID-19 and demonstrates how to sustain high rates of vaccination in a resource-efficient fashion.
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spelling pubmed-87068902021-12-25 Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK Ibrahim, Dauda Kis, Zoltán Tak, Kyungjae Papathanasiou, Maria M. Kontoravdi, Cleo Chachuat, Benoît Shah, Nilay Vaccines (Basel) Article Vaccination plays a key role in reducing morbidity and mortality caused by infectious diseases, including the recent COVID-19 pandemic. However, a comprehensive approach that allows the planning of vaccination campaigns and the estimation of the resources required to deliver and administer COVID-19 vaccines is lacking. This work implements a new framework that supports the planning and delivery of vaccination campaigns. Firstly, the framework segments and priorities target populations, then estimates vaccination timeframe and workforce requirements, and lastly predicts logistics costs and facilitates the distribution of vaccines from manufacturing plants to vaccination centres. The outcomes from this study reveal the necessary resources required and their associated costs ahead of a vaccination campaign. Analysis of results shows that by integrating demand stratification, administration, and the supply chain, the synergy amongst these activities can be exploited to allow planning and cost-effective delivery of a vaccination campaign against COVID-19 and demonstrates how to sustain high rates of vaccination in a resource-efficient fashion. MDPI 2021-12-10 /pmc/articles/PMC8706890/ /pubmed/34960206 http://dx.doi.org/10.3390/vaccines9121460 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ibrahim, Dauda
Kis, Zoltán
Tak, Kyungjae
Papathanasiou, Maria M.
Kontoravdi, Cleo
Chachuat, Benoît
Shah, Nilay
Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK
title Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK
title_full Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK
title_fullStr Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK
title_full_unstemmed Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK
title_short Model-Based Planning and Delivery of Mass Vaccination Campaigns against Infectious Disease: Application to the COVID-19 Pandemic in the UK
title_sort model-based planning and delivery of mass vaccination campaigns against infectious disease: application to the covid-19 pandemic in the uk
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706890/
https://www.ncbi.nlm.nih.gov/pubmed/34960206
http://dx.doi.org/10.3390/vaccines9121460
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