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Reduced Fatty Acid Use from CD36 Deficiency Deteriorates Streptozotocin-Induced Diabetic Cardiomyopathy in Mice
Cardiac dysfunction is induced by multifactorial mechanisms in diabetes. Deranged fatty acid (FA) utilization, known as lipotoxicity, has long been postulated as one of the upstream events in the development of diabetic cardiomyopathy. CD36, a transmembrane glycoprotein, plays a major role in FA upt...
Autores principales: | Umbarawan, Yogi, Kawakami, Ryo, Syamsunarno, Mas Rizky A. A., Obinata, Hideru, Yamaguchi, Aiko, Hanaoka, Hirofumi, Hishiki, Takako, Hayakawa, Noriyo, Koitabashi, Norimichi, Sunaga, Hiroaki, Matsui, Hiroki, Kurabayashi, Masahiko, Iso, Tatsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707002/ https://www.ncbi.nlm.nih.gov/pubmed/34940639 http://dx.doi.org/10.3390/metabo11120881 |
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