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The Effect of Capsule-in-Capsule Combinations on In Vivo Disintegration in Human Volunteers: A Combined Imaging and Salivary Tracer Study
Controlling the time point and site of the release of active ingredients within the gastrointestinal tract after administration of oral delivery systems is still a challenge. In this study, the effect of the combination of small capsules (size 3) and large capsules (size 00) on the disintegration si...
Autores principales: | Rump, Adrian, Weiss, Franziska N., Schulz, Louisa, Kromrey, Marie-Luise, Scheuch, Eberhard, Tzvetkov, Mladen V., White, Tyler, Durkee, Shane, Judge, Kevin W., Jannin, Vincent, Bellamine, Aouatef, Weitschies, Werner, Grimm, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707024/ https://www.ncbi.nlm.nih.gov/pubmed/34959284 http://dx.doi.org/10.3390/pharmaceutics13122002 |
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