Predictors of Efavirenz Plasma Exposure, Auto-Induction Profile, and Effect of Pharmacogenetic Variations among HIV-Infected Children in Ethiopia: A Prospective Cohort Study

(1) Background: Efavirenz plasma concentration displays wide between-patient variability partly due to pharmacogenetic variation and autoinduction. Pediatric data on efavirenz pharmacokinetics and the relevance of pharmacogenetic variation are scarce, particularly from sub-Saharan Africa, where >...

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Detalles Bibliográficos
Autores principales: Chala, Adugna, Tadesse, Birkneh Tilahun, Chaka, Tolossa Eticha, Mukonzo, Jackson, Kitabi, Eliford Ngaimisi, Tadesse, Sintayehu, Pohanka, Anton, Makonnen, Eyasu, Aklillu, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707067/
https://www.ncbi.nlm.nih.gov/pubmed/34945777
http://dx.doi.org/10.3390/jpm11121303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707067/
https://www.ncbi.nlm.nih.gov/pubmed/34945777
http://dx.doi.org/10.3390/jpm11121303

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