Cargando…

Formulation and Evaluation of Kaempferol Loaded Nanoparticles against Experimentally Induced Hepatocellular Carcinoma: In Vitro and In Vivo Studies

The present study was designed to prepare Kaempferol loaded nanoparticles (KFP-Np) and evaluate hepatoprotective and antioxidant effects in hepatocellular carcinoma models. KFP was encapsulated with hydroxypropyl methylcellulose acetate succinate (HPMC-AS) and Kollicoat MAE 30 DP polymers to prepare...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kazmi, Imran, Al-Abbasi, Fahad A., Afzal, Muhammad, Altayb, Hisham N., Nadeem, Muhammad Shahid, Gupta, Gaurav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707119/ https://www.ncbi.nlm.nih.gov/pubmed/34959368 http://dx.doi.org/10.3390/pharmaceutics13122086

Ejemplares similares

Correction: Kazmi et al. Formulation and Evaluation of Kaempferol Loaded Nanoparticles against Experimentally Induced Hepatocellular Carcinoma: In Vitro and In Vivo Studies. Pharmaceutics 2021, 13, 2086
por: Kazmi, Imran, et al.
Publicado: (2022)

Formulation and Evaluation of Apigenin-Loaded Hybrid Nanoparticles
por: Kazmi, Imran, et al.
Publicado: (2022)

Formulation of Piperine Nanoparticles: In Vitro Breast Cancer Cell Line and In Vivo Evaluation
por: Kazmi, Imran, et al.
Publicado: (2022)

Formulation, Optimization and Evaluation of Luteolin-Loaded Topical Nanoparticulate Delivery System for the Skin Cancer
por: Kazmi, Imran, et al.
Publicado: (2021)

Phosphodiesterase-4 Inhibitor Roflumilast-Mediated Protective Effect in Sepsis-Induced Late-Phase Event of Acute Kidney Injury: A Narrative Review
por: Kazmi, Imran, et al.
Publicado: (2022)

Sterubin protects against chemically-induced Alzheimer’s disease by reducing biomarkers of inflammation- IL-6/ IL-β/ TNF-α and oxidative stress- SOD/MDA in rats
por: Kazmi, Imran, et al.
Publicado: (2023)

Fustin Ameliorates Elevated Levels of Leptin, Adiponectin, Serum TNF-α, and Intracellular Oxidative Free Radicals in High-Fat Diet and Streptozotocin-Induced Diabetic Rats
por: Gilani, Sadaf Jamal, et al.
Publicado: (2021)

Fustin ameliorates hyperglycemia in streptozotocin induced type-2 diabetes via modulating glutathione/Superoxide dismutase/Catalase expressions, suppress lipid peroxidation and regulates histopathological changes
por: Jamal Gilani, Sadaf, et al.
Publicado: (2021)

Genomic Analysis of Multidrug-Resistant Hypervirulent (Hypermucoviscous) Klebsiella pneumoniae Strain Lacking the Hypermucoviscous Regulators (rmpA/rmpA2)
por: Altayb, Hisham N., et al.
Publicado: (2022)

Co-Occurrence of β-Lactam and Aminoglycoside Resistance Determinants among Clinical and Environmental Isolates of Klebsiella pneumoniae and Escherichia coli: A Genomic Approach
por: Altayb, Hisham N., et al.
Publicado: (2022)

Whole-Genome Sequence of Multidrug-Resistant Methicillin-Resistant Staphylococcus epidermidis Carrying Biofilm-Associated Genes and a Unique Composite of SCCmec
por: Altayb, Hisham N., et al.
Publicado: (2022)

Role of platelet rich plasma mediated repair and regeneration of cell in early stage of cardiac injury
por: Imam, Syed Sarim, et al.
Publicado: (2022)

Protective Effect of Hirsutidin against Rotenone-Induced Parkinsonism via Inhibition of Caspase-3/Interleukins-6 and 1β
por: Shahid Nadeem, Muhammad, et al.
Publicado: (2023)

Sodium-Glucose Cotransporter-2 Inhibitors Improve Cardiovascular Dysfunction in Type 2 Diabetic East Asians
por: Afzal, Muhammad, et al.
Publicado: (2021)

Formulation, Optimization and Evaluation of Cytarabine-Loaded Iron Oxide Nanoparticles: From In Vitro to In Vivo Evaluation of Anticancer Activity
por: Fule, Ritesh, et al.
Publicado: (2022)

Development of Kaempferol-Loaded Gelatin Nanoparticles for the Treatment of Corneal Neovascularization in Mice
por: Chuang, Yu-Lun, et al.
Publicado: (2019)

Fabrication, optimization, and characterization of umbelliferone β-D-galactopyranoside-loaded PLGA nanoparticles in treatment of hepatocellular carcinoma: in vitro and in vivo studies
por: Kumar, Vikas, et al.
Publicado: (2017)

Formulation, Optimization, In Vitro and In Vivo Evaluation of Saxagliptin-Loaded Lipospheres for an Improved Pharmacokinetic Behavior
por: Rasul, Akhtar, et al.
Publicado: (2021)

Utilization of Gelling Polymer to Formulate Nanoparticles Loaded with Epalrestat-Cyclodextrin Inclusion Complex: Formulation, Characterization, In-Silico Modelling and In-Vivo Toxicity Evaluation
por: Alvi, Zunaira, et al.
Publicado: (2021)

In-vitro and in-silico antibacterial activity of Azadirachta indica (Neem), methanolic extract, and identification of Beta.d-Mannofuranoside as a promising antibacterial agent
por: Altayb, Hisham N., et al.
Publicado: (2022)

Rosinidin Flavonoid Ameliorates Hyperglycemia, Lipid Pathways and Proinflammatory Cytokines in Streptozotocin-Induced Diabetic Rats
por: Gilani, Sadaf Jamal, et al.
Publicado: (2022)

Antiamnesic Potential of Malvidin on Aluminum Chloride Activated by the Free Radical Scavenging Property
por: Gilani, Sadaf Jamal, et al.
Publicado: (2022)

Current Overview on Therapeutic Potential of Vitamin D in Inflammatory Lung Diseases
por: Afzal, Muhammad, et al.
Publicado: (2021)

Formulation Development and In Vitro/In Vivo Characterization of Methotrexate-Loaded Nanoemulsion Gel Formulations for Enhanced Topical Delivery
por: Latif, Muhammad Shahid, et al.
Publicado: (2022)

Kaempferol: A Key Emphasis to Its Anticancer Potential
por: Imran, Muhammad, et al.
Publicado: (2019)

Protective Effect of Fustin Against Ethanol-Activated Gastric Ulcer via Downregulation of Biochemical Parameters in Rats
por: Gilani, Sadaf Jamal, et al.
Publicado: (2022)

Rosinidin Protects against Cisplatin-Induced Nephrotoxicity via Subsiding Proinflammatory and Oxidative Stress Biomarkers in Rats
por: Gilani, Sadaf Jamal, et al.
Publicado: (2022)

Antioxidant Role of Kaempferol in Prevention of Hepatocellular Carcinoma
por: Sharma, Nidhi, et al.
Publicado: (2021)

Nanoparticles in Drug Delivery: From History to Therapeutic Applications
por: Afzal, Obaid, et al.
Publicado: (2022)

Allicin, an Antioxidant and Neuroprotective Agent, Ameliorates Cognitive Impairment
por: Nadeem, Muhammad Shahid, et al.
Publicado: (2021)

Pharmaco-Technical Evaluation of Statistically Formulated and Optimized Dual Drug-Loaded Silica Nanoparticles for Improved Antifungal Efficacy and Wound Healing
por: Masood, Amna, et al.
Publicado: (2021)

Kaempferol-loaded bioactive glass-based scaffold for bone tissue engineering: in vitro and in vivo evaluation
por: Ranjbar, Faezeh Esmaeili, et al.
Publicado: (2023)

Cationic Solid Lipid Nanoparticles of Resveratrol for Hepatocellular Carcinoma Treatment: Systematic Optimization, in vitro Characterization and Preclinical Investigation
por: Rahman, Mahfoozur, et al.
Publicado: (2020)

Europinidin Inhibits Rotenone-Activated Parkinson’s Disease in Rodents by Decreasing Lipid Peroxidation and Inflammatory Cytokines Pathways
por: Altharawi, Ali, et al.
Publicado: (2022)

Barbigerone Potentially Alleviates Rotenone-Activated Parkinson’s Disease in a Rodent Model by Reducing Oxidative Stress and Neuroinflammatory Cytokines
por: Alharthy, Khalid M., et al.
Publicado: (2023)

Design, Synthesis, and Bioevaluation of Indole Core Containing 2-Arylidine Derivatives of Thiazolopyrimidine as Multitarget Inhibitors of Cholinesterases and Monoamine Oxidase A/B for the Treatment of Alzheimer Disease
por: Shahid Nadeem, Muhammad, et al.
Publicado: (2022)

Formulation and evaluation of sustained release matrix tablet of rabeprazole using wet granulation technique
por: Khan, Ruqaiyah, et al.
Publicado: (2014)

Comparison of Doxorubicin Anticancer Drug Loading on Different Metal Oxide Nanoparticles
por: Javed, Khalid Rashid, et al.
Publicado: (2015)

Kaempferol and Kaempferol Rhamnosides with Depigmenting and Anti-Inflammatory Properties
por: Rho, Ho Sik, et al.
Publicado: (2011)

Formulation and Optimization of Alogliptin-Loaded Polymeric Nanoparticles: In Vitro to In Vivo Assessment
por: Mohanty, Dibyalochan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sqpnfk784vil1lnnn2he976bus