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Computational Analysis of Genetic Code Variations Optimized for the Robustness against Point Mutations with Wobble-like Effects

It is believed that the codon–amino acid assignments of the standard genetic code (SGC) help to minimize the negative effects caused by point mutations. All possible point mutations of the genetic code can be represented as a weighted graph with weights that correspond to the probabilities of these...

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Detalles Bibliográficos
Autores principales: Fimmel, Elena, Gumbel, Markus, Starman, Martin, Strüngmann, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707135/
https://www.ncbi.nlm.nih.gov/pubmed/34947869
http://dx.doi.org/10.3390/life11121338