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Algal and Cyanobacterial Lectins and Their Antimicrobial Properties

Lectins are proteins with a remarkably high affinity and specificity for carbohydrates. Many organisms naturally produce them, including animals, plants, fungi, protists, bacteria, archaea, and viruses. The present report focuses on lectins produced by marine or freshwater organisms, in particular a...

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Autores principales: Fernández Romero, José Abel, Paglini, María Gabriela, Priano, Christine, Koroch, Adolfina, Rodríguez, Yoel, Sailer, James, Teleshova, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707200/
https://www.ncbi.nlm.nih.gov/pubmed/34940686
http://dx.doi.org/10.3390/md19120687
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author Fernández Romero, José Abel
Paglini, María Gabriela
Priano, Christine
Koroch, Adolfina
Rodríguez, Yoel
Sailer, James
Teleshova, Natalia
author_facet Fernández Romero, José Abel
Paglini, María Gabriela
Priano, Christine
Koroch, Adolfina
Rodríguez, Yoel
Sailer, James
Teleshova, Natalia
author_sort Fernández Romero, José Abel
collection PubMed
description Lectins are proteins with a remarkably high affinity and specificity for carbohydrates. Many organisms naturally produce them, including animals, plants, fungi, protists, bacteria, archaea, and viruses. The present report focuses on lectins produced by marine or freshwater organisms, in particular algae and cyanobacteria. We explore their structure, function, classification, and antimicrobial properties. Furthermore, we look at the expression of lectins in heterologous systems and the current research on the preclinical and clinical evaluation of these fascinating molecules. The further development of these molecules might positively impact human health, particularly the prevention or treatment of diseases caused by pathogens such as human immunodeficiency virus, influenza, and severe acute respiratory coronaviruses, among others.
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spelling pubmed-87072002021-12-25 Algal and Cyanobacterial Lectins and Their Antimicrobial Properties Fernández Romero, José Abel Paglini, María Gabriela Priano, Christine Koroch, Adolfina Rodríguez, Yoel Sailer, James Teleshova, Natalia Mar Drugs Review Lectins are proteins with a remarkably high affinity and specificity for carbohydrates. Many organisms naturally produce them, including animals, plants, fungi, protists, bacteria, archaea, and viruses. The present report focuses on lectins produced by marine or freshwater organisms, in particular algae and cyanobacteria. We explore their structure, function, classification, and antimicrobial properties. Furthermore, we look at the expression of lectins in heterologous systems and the current research on the preclinical and clinical evaluation of these fascinating molecules. The further development of these molecules might positively impact human health, particularly the prevention or treatment of diseases caused by pathogens such as human immunodeficiency virus, influenza, and severe acute respiratory coronaviruses, among others. MDPI 2021-12-01 /pmc/articles/PMC8707200/ /pubmed/34940686 http://dx.doi.org/10.3390/md19120687 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Fernández Romero, José Abel
Paglini, María Gabriela
Priano, Christine
Koroch, Adolfina
Rodríguez, Yoel
Sailer, James
Teleshova, Natalia
Algal and Cyanobacterial Lectins and Their Antimicrobial Properties
title Algal and Cyanobacterial Lectins and Their Antimicrobial Properties
title_full Algal and Cyanobacterial Lectins and Their Antimicrobial Properties
title_fullStr Algal and Cyanobacterial Lectins and Their Antimicrobial Properties
title_full_unstemmed Algal and Cyanobacterial Lectins and Their Antimicrobial Properties
title_short Algal and Cyanobacterial Lectins and Their Antimicrobial Properties
title_sort algal and cyanobacterial lectins and their antimicrobial properties
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707200/
https://www.ncbi.nlm.nih.gov/pubmed/34940686
http://dx.doi.org/10.3390/md19120687
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