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Algal and Cyanobacterial Lectins and Their Antimicrobial Properties
Lectins are proteins with a remarkably high affinity and specificity for carbohydrates. Many organisms naturally produce them, including animals, plants, fungi, protists, bacteria, archaea, and viruses. The present report focuses on lectins produced by marine or freshwater organisms, in particular a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707200/ https://www.ncbi.nlm.nih.gov/pubmed/34940686 http://dx.doi.org/10.3390/md19120687 |
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author | Fernández Romero, José Abel Paglini, María Gabriela Priano, Christine Koroch, Adolfina Rodríguez, Yoel Sailer, James Teleshova, Natalia |
author_facet | Fernández Romero, José Abel Paglini, María Gabriela Priano, Christine Koroch, Adolfina Rodríguez, Yoel Sailer, James Teleshova, Natalia |
author_sort | Fernández Romero, José Abel |
collection | PubMed |
description | Lectins are proteins with a remarkably high affinity and specificity for carbohydrates. Many organisms naturally produce them, including animals, plants, fungi, protists, bacteria, archaea, and viruses. The present report focuses on lectins produced by marine or freshwater organisms, in particular algae and cyanobacteria. We explore their structure, function, classification, and antimicrobial properties. Furthermore, we look at the expression of lectins in heterologous systems and the current research on the preclinical and clinical evaluation of these fascinating molecules. The further development of these molecules might positively impact human health, particularly the prevention or treatment of diseases caused by pathogens such as human immunodeficiency virus, influenza, and severe acute respiratory coronaviruses, among others. |
format | Online Article Text |
id | pubmed-8707200 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87072002021-12-25 Algal and Cyanobacterial Lectins and Their Antimicrobial Properties Fernández Romero, José Abel Paglini, María Gabriela Priano, Christine Koroch, Adolfina Rodríguez, Yoel Sailer, James Teleshova, Natalia Mar Drugs Review Lectins are proteins with a remarkably high affinity and specificity for carbohydrates. Many organisms naturally produce them, including animals, plants, fungi, protists, bacteria, archaea, and viruses. The present report focuses on lectins produced by marine or freshwater organisms, in particular algae and cyanobacteria. We explore their structure, function, classification, and antimicrobial properties. Furthermore, we look at the expression of lectins in heterologous systems and the current research on the preclinical and clinical evaluation of these fascinating molecules. The further development of these molecules might positively impact human health, particularly the prevention or treatment of diseases caused by pathogens such as human immunodeficiency virus, influenza, and severe acute respiratory coronaviruses, among others. MDPI 2021-12-01 /pmc/articles/PMC8707200/ /pubmed/34940686 http://dx.doi.org/10.3390/md19120687 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Fernández Romero, José Abel Paglini, María Gabriela Priano, Christine Koroch, Adolfina Rodríguez, Yoel Sailer, James Teleshova, Natalia Algal and Cyanobacterial Lectins and Their Antimicrobial Properties |
title | Algal and Cyanobacterial Lectins and Their Antimicrobial Properties |
title_full | Algal and Cyanobacterial Lectins and Their Antimicrobial Properties |
title_fullStr | Algal and Cyanobacterial Lectins and Their Antimicrobial Properties |
title_full_unstemmed | Algal and Cyanobacterial Lectins and Their Antimicrobial Properties |
title_short | Algal and Cyanobacterial Lectins and Their Antimicrobial Properties |
title_sort | algal and cyanobacterial lectins and their antimicrobial properties |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707200/ https://www.ncbi.nlm.nih.gov/pubmed/34940686 http://dx.doi.org/10.3390/md19120687 |
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