Nucleocapsid (N) Gene Mutations of SARS-CoV-2 Can Affect Real-Time RT-PCR Diagnostic and Impact False-Negative Results

The current COVID-19 pandemic demands massive testing by Real-time RT-PCR (Reverse Transcription Polymerase Chain Reaction), which is considered the gold standard diagnostic test for the detection of the SARS-CoV-2 virus. However, the virus continues to evolve with mutations that lead to phenotypic...

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Detalles Bibliográficos
Autores principales: Lesbon, Jéssika Cristina Chagas, Poleti, Mirele Daiana, de Mattos Oliveira, Elisângela Chicaroni, Patané, José Salvatore Leister, Clemente, Luan Gaspar, Viala, Vincent Louis, Ribeiro, Gabriela, Giovanetti, Marta, de Alcantara, Luiz Carlos Junior, Teixeira, Olivia, Nonato, Maria Cristina, de Lima, Loyze Paola Oliveira, Martins, Antonio Jorge, dos Santos Barros, Claudia Renata, Marqueze, Elaine Cristina, de Souza Todão Bernardino, Jardelina, Moretti, Debora Botequio, Brassaloti, Ricardo Augusto, de Lello Rocha Campos Cassano, Raquel, Mariani, Pilar Drummond Sampaio Correa, Slavov, Svetoslav Nanev, dos Santos, Rafael Bezerra, Rodrigues, Evandra Strazza, Santos, Elaine Vieira, Borges, Josiane Serrano, de La Roque, Debora Glenda Lima, Kitajima, Joao Paulo, Santos, Bibiana, Assato, Patricia Akemi, da Silva da Costa, Felipe Allan, Banho, Cecilia Artico, Sacchetto, Livia, Moraes, Marilia Mazzi, Palmieri, Melissa, da Silva, Fabiana Erica Vilanova, Grotto, Rejane Maria Tommasini, Souza-Neto, Jayme A., Nogueira, Mauricio Lacerda, Coutinho, Luiz Lehman, Calado, Rodrigo Tocantins, Neto, Raul Machado, Covas, Dimas Tadeu, Kashima, Simone, Elias, Maria Carolina, Sampaio, Sandra Coccuzzo, Fukumasu, Heidge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707239/
https://www.ncbi.nlm.nih.gov/pubmed/34960743
http://dx.doi.org/10.3390/v13122474

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