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Composite Materials Based on Iron Oxide Nanoparticles and Polyurethane for Improving the Quality of MRI

Polyether urethane (PU)-based magnetic composite materials, containing different types and concentrations of iron oxide nanostructures (Fe(2)O(3) and Fe(3)O(4)), were prepared and investigated as a novel composite platform that could be explored in different applications, especially for the improvem...

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Autores principales: Gradinaru, Luiza Madalina, Barbalata Mandru, Mihaela, Drobota, Mioara, Aflori, Magdalena, Butnaru, Maria, Spiridon, Maria, Doroftei, Florica, Aradoaei, Mihaela, Ciobanu, Romeo Cristian, Vlad, Stelian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707354/
https://www.ncbi.nlm.nih.gov/pubmed/34960867
http://dx.doi.org/10.3390/polym13244316
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author Gradinaru, Luiza Madalina
Barbalata Mandru, Mihaela
Drobota, Mioara
Aflori, Magdalena
Butnaru, Maria
Spiridon, Maria
Doroftei, Florica
Aradoaei, Mihaela
Ciobanu, Romeo Cristian
Vlad, Stelian
author_facet Gradinaru, Luiza Madalina
Barbalata Mandru, Mihaela
Drobota, Mioara
Aflori, Magdalena
Butnaru, Maria
Spiridon, Maria
Doroftei, Florica
Aradoaei, Mihaela
Ciobanu, Romeo Cristian
Vlad, Stelian
author_sort Gradinaru, Luiza Madalina
collection PubMed
description Polyether urethane (PU)-based magnetic composite materials, containing different types and concentrations of iron oxide nanostructures (Fe(2)O(3) and Fe(3)O(4)), were prepared and investigated as a novel composite platform that could be explored in different applications, especially for the improvement of the image quality of MRI investigations. Firstly, the PU structure was synthetized by means of a polyaddition reaction and then hematite (Fe(2)O(3)) and magnetite (Fe(3)O(4)) nanoparticles were added to the PU matrices to prepare magnetic nanocomposites. The type and amount of iron oxide nanoparticles influenced its structural, morphological, mechanical, dielectric, and magnetic properties. Thus, the morphology and wettability of the PU nanocomposites surfaces presented different behaviours depending on the amount of the iron oxide nanoparticles embedded in the matrices. Mechanical, dielectric, and magnetic properties were enhanced in the composites’ samples when compared with pristine PU matrix. In addition, the investigation of in vitro cytocompatibility of prepared PU nanocomposites showed that these samples are good candidates for biomedical applications, with cell viability levels in the range of 80–90%. Considering all the investigations, we can conclude that the addition of magnetic particles introduced additional properties to the composite, which could significantly expand the functionality of the materials developed in this work.
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spelling pubmed-87073542021-12-25 Composite Materials Based on Iron Oxide Nanoparticles and Polyurethane for Improving the Quality of MRI Gradinaru, Luiza Madalina Barbalata Mandru, Mihaela Drobota, Mioara Aflori, Magdalena Butnaru, Maria Spiridon, Maria Doroftei, Florica Aradoaei, Mihaela Ciobanu, Romeo Cristian Vlad, Stelian Polymers (Basel) Article Polyether urethane (PU)-based magnetic composite materials, containing different types and concentrations of iron oxide nanostructures (Fe(2)O(3) and Fe(3)O(4)), were prepared and investigated as a novel composite platform that could be explored in different applications, especially for the improvement of the image quality of MRI investigations. Firstly, the PU structure was synthetized by means of a polyaddition reaction and then hematite (Fe(2)O(3)) and magnetite (Fe(3)O(4)) nanoparticles were added to the PU matrices to prepare magnetic nanocomposites. The type and amount of iron oxide nanoparticles influenced its structural, morphological, mechanical, dielectric, and magnetic properties. Thus, the morphology and wettability of the PU nanocomposites surfaces presented different behaviours depending on the amount of the iron oxide nanoparticles embedded in the matrices. Mechanical, dielectric, and magnetic properties were enhanced in the composites’ samples when compared with pristine PU matrix. In addition, the investigation of in vitro cytocompatibility of prepared PU nanocomposites showed that these samples are good candidates for biomedical applications, with cell viability levels in the range of 80–90%. Considering all the investigations, we can conclude that the addition of magnetic particles introduced additional properties to the composite, which could significantly expand the functionality of the materials developed in this work. MDPI 2021-12-09 /pmc/articles/PMC8707354/ /pubmed/34960867 http://dx.doi.org/10.3390/polym13244316 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gradinaru, Luiza Madalina
Barbalata Mandru, Mihaela
Drobota, Mioara
Aflori, Magdalena
Butnaru, Maria
Spiridon, Maria
Doroftei, Florica
Aradoaei, Mihaela
Ciobanu, Romeo Cristian
Vlad, Stelian
Composite Materials Based on Iron Oxide Nanoparticles and Polyurethane for Improving the Quality of MRI
title Composite Materials Based on Iron Oxide Nanoparticles and Polyurethane for Improving the Quality of MRI
title_full Composite Materials Based on Iron Oxide Nanoparticles and Polyurethane for Improving the Quality of MRI
title_fullStr Composite Materials Based on Iron Oxide Nanoparticles and Polyurethane for Improving the Quality of MRI
title_full_unstemmed Composite Materials Based on Iron Oxide Nanoparticles and Polyurethane for Improving the Quality of MRI
title_short Composite Materials Based on Iron Oxide Nanoparticles and Polyurethane for Improving the Quality of MRI
title_sort composite materials based on iron oxide nanoparticles and polyurethane for improving the quality of mri
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707354/
https://www.ncbi.nlm.nih.gov/pubmed/34960867
http://dx.doi.org/10.3390/polym13244316
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