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Identification of Phytoconstituents as Potent Inhibitors of Casein Kinase-1 Alpha Using Virtual Screening and Molecular Dynamics Simulations

Casein kinase-1 alpha (CK1α) is a multifunctional protein kinase that belongs to the serine/threonine kinases of the CK1α family. It is involved in various signaling pathways associated with chromosome segregation, cell metabolism, cell cycle progression, apoptosis, autophagy, etc. It has been known...

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Detalles Bibliográficos
Autores principales:	Shafie, Alaa, Khan, Shama, Zehra, Mohammad, Taj, Anjum, Farah, Hasan, Gulam Mustafa, Yadav, Dharmendra Kumar, Hassan, Md. Imtaiyaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707374/ https://www.ncbi.nlm.nih.gov/pubmed/34959438 http://dx.doi.org/10.3390/pharmaceutics13122157

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