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HIV-1 Packaging Visualised by In-Gel SHAPE

HIV-1 packages two copies of its gRNA into virions via an interaction with the viral structural protein Gag. Both copies and their native RNA structure are essential for virion infectivity. The precise stepwise nature of the packaging process has not been resolved. This is largely due to a prior lac...

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Detalles Bibliográficos
Autores principales: D’Souza, Aaron R., Jayaraman, Dhivya, Long, Ziqi, Zeng, Jingwei, Prestwood, Liam J., Chan, Charlene, Kappei, Dennis, Lever, Andrew M. L., Kenyon, Julia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707378/
https://www.ncbi.nlm.nih.gov/pubmed/34960658
http://dx.doi.org/10.3390/v13122389