Two-Chains Tissue Plasminogen Activator Unifies Met and NMDA Receptor Signalling to Control Neuronal Survival

Tissue-type plasminogen activator (tPA) plays roles in the development and the plasticity of the nervous system. Here, we demonstrate in neurons, that by opposition to the single chain form (sc-tPA), the two-chains form of tPA (tc-tPA) activates the MET receptor, leading to the recruitment of N-Meth...

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Detalles Bibliográficos
Autores principales: Hedou, Elodie, Douceau, Sara, Chevilley, Arnaud, Varangot, Alexandre, Thiebaut, Audrey M., Triniac, Hortense, Bardou, Isabelle, Ali, Carine, Maillasson, Mike, Crepaldi, Tiziana, Comoglio, Paolo, Lemarchand, Eloïse, Agin, Véronique, Roussel, Benoit D., Vivien, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707453/
https://www.ncbi.nlm.nih.gov/pubmed/34948279
http://dx.doi.org/10.3390/ijms222413483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707453/
https://www.ncbi.nlm.nih.gov/pubmed/34948279
http://dx.doi.org/10.3390/ijms222413483

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