In Vitro and In Vivo Inhibition of MATE1 by Tyrosine Kinase Inhibitors

The membrane transport of many cationic prescription drugs depends on facilitated transport by organic cation transporters of which several members, including OCT2 (SLC22A2), are sensitive to inhibition by select tyrosine kinase inhibitors (TKIs). We hypothesized that TKIs may differentially interac...

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Detalles Bibliográficos
Autores principales: Uddin, Muhammad Erfan, Talebi, Zahra, Chen, Sijie, Jin, Yan, Gibson, Alice A., Noonan, Anne M., Cheng, Xiaolin, Hu, Shuiying, Sparreboom, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707461/
https://www.ncbi.nlm.nih.gov/pubmed/34959286
http://dx.doi.org/10.3390/pharmaceutics13122004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707461/
https://www.ncbi.nlm.nih.gov/pubmed/34959286
http://dx.doi.org/10.3390/pharmaceutics13122004

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