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In Vitro and In Vivo Inhibition of MATE1 by Tyrosine Kinase Inhibitors
The membrane transport of many cationic prescription drugs depends on facilitated transport by organic cation transporters of which several members, including OCT2 (SLC22A2), are sensitive to inhibition by select tyrosine kinase inhibitors (TKIs). We hypothesized that TKIs may differentially interac...
Autores principales: | Uddin, Muhammad Erfan, Talebi, Zahra, Chen, Sijie, Jin, Yan, Gibson, Alice A., Noonan, Anne M., Cheng, Xiaolin, Hu, Shuiying, Sparreboom, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707461/ https://www.ncbi.nlm.nih.gov/pubmed/34959286 http://dx.doi.org/10.3390/pharmaceutics13122004 |
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