Cargando…

Ru(III) Complexes with Lonidamine-Modified Ligands

A series of bifunctional Ru(III) complexes with lonidamine-modified ligands (lonidamine is a selective inhibitor of aerobic glycolysis in cancer cells) was described. Redox properties of Ru(III) complexes were characterized by cyclic voltammetry. An easy reduction suggested a perspective for these a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shutkov, Ilya A., Okulova, Yulia N., Tyurin, Vladimir Yu., Sokolova, Elena V., Babkov, Denis A., Spasov, Alexander A., Gracheva, Yulia A., Schmidt, Claudia, Kirsanov, Kirill I., Shtil, Alexander A., Redkozubova, Olga M., Shevtsova, Elena F., Milaeva, Elena R., Ott, Ingo, Nazarov, Alexey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707700/ https://www.ncbi.nlm.nih.gov/pubmed/34948263 http://dx.doi.org/10.3390/ijms222413468

Ejemplares similares

New Organometallic Ru(II) Compounds with Lonidamine Motif as Antitumor Agents
por: Shutkov, Ilya A., et al.
Publicado: (2023)

Biological Activity of Novel Organotin Compounds with a Schiff Base Containing an Antioxidant Fragment
por: Antonenko, Taisiya A., et al.
Publicado: (2023)

Protective Effect of Meso-Tetrakis-(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin on the In Vivo Impact of Trimethyltin Chloride on the Antioxidative Defense System
por: Milaeva, Elena R., et al.
Publicado: (2006)

Cytotoxic and Luminescent Properties of Novel Organotin Complexes with Chelating Antioxidant Ligand
por: Nikitin, Evgeny, et al.
Publicado: (2022)

Amino Derivatives of Diaryl Pyrimidines and Azolopyrimidines as Protective Agents against LPS-Induced Acute Lung Injury
por: Spasov, Alexander, et al.
Publicado: (2023)

Verubulin (Azixa) Analogues with Increased Saturation: Synthesis, SAR and Encapsulation in Biocompatible Nanocontainers Based on Ca(2+) or Mg(2+) Cross-Linked Alginate
por: Sedenkova, Kseniya N., et al.
Publicado: (2023)

Discovery of Nitro-azolo[1,5-a]pyrimidines with Anti-Inflammatory and Protective Activity against LPS-Induced Acute Lung Injury
por: Spasov, Alexander, et al.
Publicado: (2022)

Evaluation of Cytotoxicity and α-Glucosidase Inhibitory Activity of Amide and Polyamino-Derivatives of Lupane Triterpenoids
por: Kazakova, Oxana B., et al.
Publicado: (2020)

New Molecules of Diterpene Origin with Inhibitory Properties toward α-Glucosidase
por: Tretyakova, Elena, et al.
Publicado: (2022)

Inhibition of Mitochondrial Complex II by the Anticancer Agent Lonidamine
por: Guo, Lili, et al.
Publicado: (2016)

Guanidine Derivatives of Quinazoline-2,4(1H,3H)-Dione as NHE-1 Inhibitors and Anti-Inflammatory Agents
por: Spasov, Alexander, et al.
Publicado: (2022)

6-(Tetrazol-5-yl)-7-aminoazolo[1,5-a]pyrimidines as Novel Potent CK2 Inhibitors
por: Urakov, Grigoriy V., et al.
Publicado: (2022)

Microwave-Assisted Synthesis of 3-Hydroxy-2-oxindoles and Pilot Evaluation of Their Antiglaucomic Activity
por: Efremov, Alexander M., et al.
Publicado: (2023)

Influence of the Number of Axial Bexarotene Ligands on the Cytotoxicity of Pt(IV) Analogs of Oxaliplatin
por: Nosova, Yulia N., et al.
Publicado: (2017)

3-Arylidene-2-oxindoles as Potent NRH:Quinone Oxidoreductase 2 Inhibitors
por: Lozinskaya, Natalia A., et al.
Publicado: (2023)

Bicyclic Isoxazoline Derivatives: Synthesis and Evaluation of Biological Activity
por: Sedenkova, Kseniya N., et al.
Publicado: (2022)

Potentiation of Cisplatin Cytotoxicity in Resistant Ovarian Cancer SKOV3/Cisplatin Cells by Quercetin Pre-Treatment
por: Hasan, Aseel Ali, et al.
Publicado: (2023)

3-Arylidene-2-oxindoles as GSK3β inhibitors and anti-thrombotic agents
por: Babkov, Denis, et al.
Publicado: (2023)

Phase II study of lonidamine in metastatic breast cancer.
por: Pronzato, P., et al.
Publicado: (1989)

Inhibition of the recovery from potentially lethal damage by lonidamine.
por: Hahn, G. M., et al.
Publicado: (1984)

Reversal of adriamycin resistance by lonidamine in a human breast cancer cell line.
por: Citro, G., et al.
Publicado: (1991)

Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis
por: Cheng, Gang, et al.
Publicado: (2019)

The Potential of Lonidamine in Combination with Chemotherapy and Physical Therapy in Cancer Treatment
por: Huang, Yaxin, et al.
Publicado: (2020)

Directly targeting ASC by lonidamine alleviates inflammasome-driven diseases
por: Chen, Chen, et al.
Publicado: (2022)

Effect of lonidamine derivatives on the inhibition of transformed cell area expansion
por: Aoyama, Megumi, et al.
Publicado: (2023)

Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety
por: Burmistrov, Vladimir, et al.
Publicado: (2022)

Effect of Differences in Metabolic Activity of Melanoma Models on Response to Lonidamine plus Doxorubicin
por: Nath, Kavindra, et al.
Publicado: (2018)

A phase II clinical and pharmacokinetic study of Lonidamine in patients with advanced breast cancer.
por: Mansi, J. L., et al.
Publicado: (1991)

Amplification of anticancer efficacy by co-delivery of doxorubicin and lonidamine with extracellular vesicles
por: Li, Huizhen, et al.
Publicado: (2022)

Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine
por: Gong, Shengnan, et al.
Publicado: (2023)

The lonidamine derivative H2-gamendazole reduces cyst formation in polycystic kidney disease
por: Sundar, Shirin V., et al.
Publicado: (2022)

Genetically Engineered Mice Unveil In Vivo Roles of the Mediator Complex
por: Ilchuk, Leonid A., et al.
Publicado: (2023)

Stimulation of the apoptotic response as a basis for the therapeutic synergism of lonidamine and cisplatin in combination in human tumour xenografts.
por: De Cesare, M., et al.
Publicado: (1998)

Design, Synthesis and In Vitro Biological Activity of Novel C-7 Methylene Congeners of Furanoallocolchicinoids
por: Gracheva, Iuliia A., et al.
Publicado: (2023)

Effects of lonidamine alone or combined with hyperthermia in some experimental cell and tumour systems.
por: Silvestrini, B., et al.
Publicado: (1983)

Re-programming tumour cell metabolism to treat cancer: no lone target for lonidamine
por: Bhutia, Yangzom D., et al.
Publicado: (2016)

The controllable destabilization route for synthesis of low cytotoxic magnetic nanospheres with photonic response
por: Andreeva, Yulia I., et al.
Publicado: (2017)

Phase II study of lonidamine in non-small cell lung cancer: final report.
por: Kokron, O., et al.
Publicado: (1990)

In vitro effects of lonidamine and 6-aminonicotinamide against Echinococcus granulosussensu stricto and Echinococcus multilocularis
por: Xin, Qi, et al.
Publicado: (2020)

Lonidamine and domperidone inhibit expansion of transformed cell areas by modulating motility of surrounding nontransformed cells
por: Aoyama, Megumi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jclmsu8idn03b9bqthvrjta6cj