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The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties
Background: Linen dressings were invented a few years ago but are still being worked on. Methods: The obtained fabrics from the traditional variety of flax (Nike), two transgenic types of flax (M50 and B14) and the combination of these two flax fibers (M50 + B14) were tested in direct contact in cel...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707772/ https://www.ncbi.nlm.nih.gov/pubmed/34947330 http://dx.doi.org/10.3390/ma14247736 |
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author | Gębarowski, Tomasz Jęśkowiak, Izabela Janeczek, Maciej Żuk, Magdalena Dobosz, Agnieszka Wiatrak, Benita |
author_facet | Gębarowski, Tomasz Jęśkowiak, Izabela Janeczek, Maciej Żuk, Magdalena Dobosz, Agnieszka Wiatrak, Benita |
author_sort | Gębarowski, Tomasz |
collection | PubMed |
description | Background: Linen dressings were invented a few years ago but are still being worked on. Methods: The obtained fabrics from the traditional variety of flax (Nike), two transgenic types of flax (M50 and B14) and the combination of these two flax fibers (M50 + B14) were tested in direct contact in cell cultures. Cell viability tests were performed, and the proliferation potential of cells on Balb3T3 and NHEK cell lines was checked using the Sulforhodamine-B (SRB) test. Moreover, the effect of new linen fabrics on apoptosis of THP-1 cells, as well as on the cell cycle of NHEK, HMCEV and THP-1, cells after 24 h of incubation was assessed. Results: All tested linen fabrics did not raise the number of necrotic cells. The tested fabrics caused a statistically significant decrease in the total protein content in skin cancer (except for 0.5 cm of Nike-type fabrics). The smallest cells in the apoptotic phase were in cultures treated with M50 fiber on an area of 0.5 cm. After 48 h of incubation of HEMVEC, NHEK and THP-1 cells with the tested fabrics, the growth of S-phase cells was noticed in all cases. At the same time, the greatest increase was observed with the use of B14 fabric. Necrosis is not statistically significant. Conclusions: All the obtained flax fibers in the form of flax dressings did not lose their wound-healing properties under the influence of the technological process. New dressings made of genetically modified flax are a chance to increase the effectiveness of treatment of difficult healing wounds. |
format | Online Article Text |
id | pubmed-8707772 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87077722021-12-25 The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties Gębarowski, Tomasz Jęśkowiak, Izabela Janeczek, Maciej Żuk, Magdalena Dobosz, Agnieszka Wiatrak, Benita Materials (Basel) Article Background: Linen dressings were invented a few years ago but are still being worked on. Methods: The obtained fabrics from the traditional variety of flax (Nike), two transgenic types of flax (M50 and B14) and the combination of these two flax fibers (M50 + B14) were tested in direct contact in cell cultures. Cell viability tests were performed, and the proliferation potential of cells on Balb3T3 and NHEK cell lines was checked using the Sulforhodamine-B (SRB) test. Moreover, the effect of new linen fabrics on apoptosis of THP-1 cells, as well as on the cell cycle of NHEK, HMCEV and THP-1, cells after 24 h of incubation was assessed. Results: All tested linen fabrics did not raise the number of necrotic cells. The tested fabrics caused a statistically significant decrease in the total protein content in skin cancer (except for 0.5 cm of Nike-type fabrics). The smallest cells in the apoptotic phase were in cultures treated with M50 fiber on an area of 0.5 cm. After 48 h of incubation of HEMVEC, NHEK and THP-1 cells with the tested fabrics, the growth of S-phase cells was noticed in all cases. At the same time, the greatest increase was observed with the use of B14 fabric. Necrosis is not statistically significant. Conclusions: All the obtained flax fibers in the form of flax dressings did not lose their wound-healing properties under the influence of the technological process. New dressings made of genetically modified flax are a chance to increase the effectiveness of treatment of difficult healing wounds. MDPI 2021-12-15 /pmc/articles/PMC8707772/ /pubmed/34947330 http://dx.doi.org/10.3390/ma14247736 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Gębarowski, Tomasz Jęśkowiak, Izabela Janeczek, Maciej Żuk, Magdalena Dobosz, Agnieszka Wiatrak, Benita The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties |
title | The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties |
title_full | The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties |
title_fullStr | The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties |
title_full_unstemmed | The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties |
title_short | The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties |
title_sort | technological process of obtaining new linen dressings did not cause the loss of their wound-healing properties |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707772/ https://www.ncbi.nlm.nih.gov/pubmed/34947330 http://dx.doi.org/10.3390/ma14247736 |
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