An In Vitro Assessment of Immunostimulatory Responses to Ten Model Innate Immune Response Modulating Impurities (IIRMIs) and Peptide Drug Product, Teriparatide

Understanding, predicting, and minimizing the immunogenicity of peptide-based therapeutics are of paramount importance for ensuring the safety and efficacy of these products. The so-called anti-drug antibodies (ADA) may have various clinical consequences, including but not limited to the alteration...

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Detalles Bibliográficos
Autores principales: Holley, Claire K., Cedrone, Edward, Donohue, Duncan, Neun, Barry W., Verthelyi, Daniela, Pang, Eric S., Dobrovolskaia, Marina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707785/
https://www.ncbi.nlm.nih.gov/pubmed/34946542
http://dx.doi.org/10.3390/molecules26247461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707785/
https://www.ncbi.nlm.nih.gov/pubmed/34946542
http://dx.doi.org/10.3390/molecules26247461

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