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An In Vitro Assessment of Immunostimulatory Responses to Ten Model Innate Immune Response Modulating Impurities (IIRMIs) and Peptide Drug Product, Teriparatide
Understanding, predicting, and minimizing the immunogenicity of peptide-based therapeutics are of paramount importance for ensuring the safety and efficacy of these products. The so-called anti-drug antibodies (ADA) may have various clinical consequences, including but not limited to the alteration...
Autores principales: | Holley, Claire K., Cedrone, Edward, Donohue, Duncan, Neun, Barry W., Verthelyi, Daniela, Pang, Eric S., Dobrovolskaia, Marina A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707785/ https://www.ncbi.nlm.nih.gov/pubmed/34946542 http://dx.doi.org/10.3390/molecules26247461 |
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