Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection

We present a case of immune thrombocytopenia (ITP) induced by the chimpanzee adenovirus-vectored vaccine, without evidence of thrombosis, eight days after vaccine administration. The thrombocytopenia condition improved after administering steroid treatment. This adenovirus vaccine had been reported...

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Autores principales: Liao, Po-Wei, Teng, Chieh-Lin Jerry, Chou, Cheng-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707922/
https://www.ncbi.nlm.nih.gov/pubmed/34960232
http://dx.doi.org/10.3390/vaccines9121486
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author Liao, Po-Wei
Teng, Chieh-Lin Jerry
Chou, Cheng-Wei
author_facet Liao, Po-Wei
Teng, Chieh-Lin Jerry
Chou, Cheng-Wei
author_sort Liao, Po-Wei
collection PubMed
description We present a case of immune thrombocytopenia (ITP) induced by the chimpanzee adenovirus-vectored vaccine, without evidence of thrombosis, eight days after vaccine administration. The thrombocytopenia condition improved after administering steroid treatment. This adenovirus vaccine had been reported to induce rare side effects, such as immune thrombotic thrombocytopenia. This case report showed that it could also induce immune thrombocytopenia without the presence of thrombosis. Therefore, we should be cautious of this rare side effect as global vaccine administrations against coronavirus disease increase.
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spelling pubmed-87079222021-12-25 Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection Liao, Po-Wei Teng, Chieh-Lin Jerry Chou, Cheng-Wei Vaccines (Basel) Case Report We present a case of immune thrombocytopenia (ITP) induced by the chimpanzee adenovirus-vectored vaccine, without evidence of thrombosis, eight days after vaccine administration. The thrombocytopenia condition improved after administering steroid treatment. This adenovirus vaccine had been reported to induce rare side effects, such as immune thrombotic thrombocytopenia. This case report showed that it could also induce immune thrombocytopenia without the presence of thrombosis. Therefore, we should be cautious of this rare side effect as global vaccine administrations against coronavirus disease increase. MDPI 2021-12-16 /pmc/articles/PMC8707922/ /pubmed/34960232 http://dx.doi.org/10.3390/vaccines9121486 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Liao, Po-Wei
Teng, Chieh-Lin Jerry
Chou, Cheng-Wei
Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection
title Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection
title_full Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection
title_fullStr Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection
title_full_unstemmed Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection
title_short Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection
title_sort immune thrombocytopenia induced by the chimpanzee adenovirus-vectored vaccine against sars-cov-2 infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707922/
https://www.ncbi.nlm.nih.gov/pubmed/34960232
http://dx.doi.org/10.3390/vaccines9121486
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AT chouchengwei immunethrombocytopeniainducedbythechimpanzeeadenovirusvectoredvaccineagainstsarscov2infection

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