Magnesium and Morphine in the Treatment of Chronic Neuropathic Pain–A Biomedical Mechanism of Action

The effectiveness of opioids in the treatment of neuropathic pain is limited. It was demonstrated that magnesium ions (Mg(2+)), physiological antagonists of N-methyl-D-aspartate receptor (NMDAR), increase opioid analgesia in chronic pain. Our study aimed to determine the molecular mechanism of this...

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Detalles Bibliográficos
Autores principales: Kulik, Kamila, Żyżyńska-Granica, Barbara, Kowalczyk, Agnieszka, Kurowski, Przemysław, Gajewska, Małgorzata, Bujalska-Zadrożny, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707930/
https://www.ncbi.nlm.nih.gov/pubmed/34948397
http://dx.doi.org/10.3390/ijms222413599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707930/
https://www.ncbi.nlm.nih.gov/pubmed/34948397
http://dx.doi.org/10.3390/ijms222413599

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