Cargando…
Magnesium and Morphine in the Treatment of Chronic Neuropathic Pain–A Biomedical Mechanism of Action
The effectiveness of opioids in the treatment of neuropathic pain is limited. It was demonstrated that magnesium ions (Mg(2+)), physiological antagonists of N-methyl-D-aspartate receptor (NMDAR), increase opioid analgesia in chronic pain. Our study aimed to determine the molecular mechanism of this...
Autores principales: | Kulik, Kamila, Żyżyńska-Granica, Barbara, Kowalczyk, Agnieszka, Kurowski, Przemysław, Gajewska, Małgorzata, Bujalska-Zadrożny, Magdalena |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707930/ https://www.ncbi.nlm.nih.gov/pubmed/34948397 http://dx.doi.org/10.3390/ijms222413599 |
Ejemplares similares
-
Micronized Organic Magnesium Salts Enhance Opioid Analgesia in Rats
por: Bujalska-Zadrożny, Magdalena, et al.
Publicado: (2016) -
The Positive and Negative Outcome of Morphine and Disulfiram Subacute Co-Administration in Rats in the Absence of Ethanol Challenge
por: Frączek, Karolina, et al.
Publicado: (2020) -
Novel opioid-neurotensin-based hybrid peptide with spinal long-lasting antinociceptive activity and a propensity to delay tolerance development
por: Frączek, Karolina, et al.
Publicado: (2020) -
Morphine and pregabalin in the treatment of neuropathic pain
por: Wang, Yue, et al.
Publicado: (2017) -
Treatment with dopamine β-hydroxylase (DBH) inhibitors prevents morphine use and relapse-like behavior in rats
por: Frankowska, Małgorzata, et al.
Publicado: (2021)