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Differential Effect of SARS-CoV-2 Spike Glycoprotein 1 on Human Bronchial and Alveolar Lung Mucosa Models: Implications for Pathogenicity

Background: The SARS-CoV-2 spike protein mediates attachment of the virus to the host cell receptor and fusion between the virus and the cell membrane. The S1 subunit of the spike glycoprotein (S1 protein) contains the angiotensin converting enzyme 2 (ACE2) receptor binding domain. The SARS-CoV-2 va...

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Detalles Bibliográficos
Autores principales: Rahman, Mizanur, Irmler, Martin, Keshavan, Sandeep, Introna, Micol, Beckers, Johannes, Palmberg, Lena, Johanson, Gunnar, Ganguly, Koustav, Upadhyay, Swapna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708014/
https://www.ncbi.nlm.nih.gov/pubmed/34960806
http://dx.doi.org/10.3390/v13122537