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Identification and Heterologous Expression of the Kendomycin B Biosynthetic Gene Cluster from Verrucosispora sp. SCSIO 07399

Verrucosispora sp. SCSIO 07399, a rare marine-derived actinomycete, produces a set of ansamycin-like polyketides kendomycin B–D (1–3) which possess potent antibacterial activities and moderate tumor cytotoxicity. Structurally, kendomycin B–D contain a unique aliphatic macrocyclic ansa scaffold in wh...

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Detalles Bibliográficos
Autores principales:	Chen, Jiang, Zhang, Shanwen, Chen, Yingying, Tian, Xinpeng, Gu, Yucheng, Ju, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708025/ https://www.ncbi.nlm.nih.gov/pubmed/34940672 http://dx.doi.org/10.3390/md19120673

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