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Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala
Body energy and metabolic homeostasis are exquisitely controlled by multiple, often overlapping regulatory mechanisms, which permit the tight adjustment between fuel reserves, internal needs, and environmental (e.g., nutritional) conditions. As such, this function is sensitive to and closely connect...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708157/ https://www.ncbi.nlm.nih.gov/pubmed/34940594 http://dx.doi.org/10.3390/metabo11120837 |
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author | Pineda, Rafael Torres, Encarnacion Tena-Sempere, Manuel |
author_facet | Pineda, Rafael Torres, Encarnacion Tena-Sempere, Manuel |
author_sort | Pineda, Rafael |
collection | PubMed |
description | Body energy and metabolic homeostasis are exquisitely controlled by multiple, often overlapping regulatory mechanisms, which permit the tight adjustment between fuel reserves, internal needs, and environmental (e.g., nutritional) conditions. As such, this function is sensitive to and closely connected with other relevant bodily systems, including reproduction and gonadal function. The aim of this mini-review article is to summarize the most salient experimental data supporting a role of the amygdala as a key brain region for emotional learning and behavior, including reward processing, in the physiological control of feeding and energy balance. In particular, a major focus will be placed on the putative interplay between reproductive signals and amygdala pathways, as it pertains to the control of metabolism, as complementary, extrahypothalamic circuit for the integral control of energy balance and gonadal function. |
format | Online Article Text |
id | pubmed-8708157 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87081572021-12-25 Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala Pineda, Rafael Torres, Encarnacion Tena-Sempere, Manuel Metabolites Review Body energy and metabolic homeostasis are exquisitely controlled by multiple, often overlapping regulatory mechanisms, which permit the tight adjustment between fuel reserves, internal needs, and environmental (e.g., nutritional) conditions. As such, this function is sensitive to and closely connected with other relevant bodily systems, including reproduction and gonadal function. The aim of this mini-review article is to summarize the most salient experimental data supporting a role of the amygdala as a key brain region for emotional learning and behavior, including reward processing, in the physiological control of feeding and energy balance. In particular, a major focus will be placed on the putative interplay between reproductive signals and amygdala pathways, as it pertains to the control of metabolism, as complementary, extrahypothalamic circuit for the integral control of energy balance and gonadal function. MDPI 2021-12-03 /pmc/articles/PMC8708157/ /pubmed/34940594 http://dx.doi.org/10.3390/metabo11120837 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pineda, Rafael Torres, Encarnacion Tena-Sempere, Manuel Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala |
title | Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala |
title_full | Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala |
title_fullStr | Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala |
title_full_unstemmed | Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala |
title_short | Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala |
title_sort | extrahypothalamic control of energy balance and its connection with reproduction: roles of the amygdala |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708157/ https://www.ncbi.nlm.nih.gov/pubmed/34940594 http://dx.doi.org/10.3390/metabo11120837 |
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