Cargando…

Peptide-Functionalized Dendrimer Nanocarriers for Targeted Microdystrophin Gene Delivery

Gene therapy is a good alternative for determined congenital disorders; however, there are numerous limitations for gene delivery in vivo including targeted cellular uptake, intracellular trafficking, and transport through the nuclear membrane. Here, a modified G5 polyamidoamine (G5 PAMAM) dendrimer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hersh, Jessica, Condor Capcha, José Manuel, Iansen Irion, Camila, Lambert, Guerline, Noguera, Mauricio, Singh, Mohit, Kaur, Avinash, Dikici, Emre, Jiménez, Joaquín J., Shehadeh, Lina A., Daunert, Sylvia, Deo, Sapna K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708248/ https://www.ncbi.nlm.nih.gov/pubmed/34959441 http://dx.doi.org/10.3390/pharmaceutics13122159

Ejemplares similares

Mouse Model of Heart Failure With Preserved Ejection Fraction Driven by Hyperlipidemia and Enhanced Cardiac Low‐Density Lipoprotein Receptor Expression
por: Williams, Monique, et al.
Publicado: (2022)

Nuclear Osteopontin Is a Marker of Advanced Heart Failure and Cardiac Allograft Vasculopathy: Evidence From Transplant and Retransplant Hearts
por: Irion, Camila Iansen, et al.
Publicado: (2020)

Opioid Antagonist Nanodrugs Successfully Attenuate the Severity of Ischemic Stroke
por: Peyravian, Nadia, et al.
Publicado: (2022)

Accelerating the Screening of Small Peptide Ligands by Combining Peptide-Protein Docking and Machine Learning
por: Codina, Josep-Ramon, et al.
Publicado: (2023)

Highly Sensitive and Selective Direct Detection of Zika Virus Particles in Human Bodily Fluids for Accurate Early Diagnosis of Infection
por: Pawley, Devon C., et al.
Publicado: (2019)

Metal organic framework encapsulated tamavidin-Gluc reporter: application in COVID-19 spike antigen bioluminescent immunoassay
por: Reyes, Sherwin, et al.
Publicado: (2022)

Targeted Bioluminescent Imaging of Pancreatic Ductal Adenocarcinoma Using Nanocarrier-Complexed EGFR-Binding Affibody–Gaussia Luciferase Fusion Protein
por: Hersh, Jessica, et al.
Publicado: (2023)

Nanotechnology-Driven Therapeutic Interventions in Wound Healing: Potential Uses and Applications
por: Hamdan, Suzana, et al.
Publicado: (2017)

Col4a3(-/-) Mice on Balb/C Background Have Less Severe Cardiorespiratory Phenotype and SGLT2 Over-Expression Compared to 129x1/SvJ and C57Bl/6 Backgrounds
por: Irion, Camila I., et al.
Publicado: (2022)

Truncated Variants of Gaussia Luciferase with Tyrosine Linker for Site-Specific Bioconjugate Applications
por: Hunt, Eric A., et al.
Publicado: (2016)

Generation of SARS-CoV-2 Spike Pseudotyped Virus for Viral Entry and Neutralization Assays: A 1-Week Protocol
por: Condor Capcha, Jose Manuel, et al.
Publicado: (2021)

An Intact Cell Bioluminescence-Based Assay for the Simple and Rapid Diagnosis of Urinary Tract Infection
por: Reyes, Sherwin, et al.
Publicado: (2020)

Cannabidiol as a Novel Therapeutic for Immune Modulation
por: Peyravian, Nadia, et al.
Publicado: (2020)

The Inflammatory Aspect of Male and Female Pattern Hair Loss
por: Peyravian, Nadia, et al.
Publicado: (2020)

The Anti-Inflammatory Effects of Cannabidiol (CBD) on Acne
por: Peyravian, Nadia, et al.
Publicado: (2022)

Osteopontin Expression in Cardiomyocytes Is Increased in Pediatric Patients With Sepsis or Pneumonia
por: Irion, Camila Iansen, et al.
Publicado: (2018)

Computationally Designed Peptides for Zika Virus Detection: An Incremental Construction Approach
por: Mascini, Marcello, et al.
Publicado: (2019)

Directing and Potentiating Stem Cell-Mediated Angiogenesis and Tissue Repair by Cell Surface E-Selectin Coating
por: Liu, Zhao-Jun, et al.
Publicado: (2016)

Dendrimers: A New Race of Pharmaceutical Nanocarriers
por: Mittal, Pooja, et al.
Publicado: (2021)

Dendrimer nanocarriers drug action: perspective for neuronal pharmacology
por: Vidal, Felipe, et al.
Publicado: (2015)

New Ways to Treat Tuberculosis Using Dendrimers as Nanocarriers
por: Mignani, Serge, et al.
Publicado: (2018)

Microdystrophin Expression as a Surrogate Endpoint for Duchenne Muscular Dystrophy Clinical Trials
por: Chamberlain, Jeffrey S., et al.
Publicado: (2023)

Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation
por: Benabdallah, Basma F, et al.
Publicado: (2013)

Dendrimer Nanocarriers for Transport Modulation Across Models of the Pulmonary Epithelium
por: Bharatwaj, Balaji, et al.
Publicado: (2014)

Dendrimers as Nanocarriers for Nucleic Acid and Drug Delivery in Cancer Therapy
por: Palmerston Mendes, Livia, et al.
Publicado: (2017)

Dendrimers as Nanocarriers for the Delivery of Drugs Obtained from Natural Products
por: An, Huan, et al.
Publicado: (2023)

Rapid isothermal point-of-care test for screening of SARS-CoV-2 (COVID-19)
por: Zingg, Jean-Marc, et al.
Publicado: (2023)

Understanding the Role and Clinical Applications of Exosomes in Gynecologic Malignancies: A Review of the Current Literature
por: Roy, Molly, et al.
Publicado: (2021)

Enhanced effect of microdystrophin gene transfection by HSV-VP22 mediated intercellular protein transport
por: Xiong, Fu, et al.
Publicado: (2007)

Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy
por: Le Guiner, Caroline, et al.
Publicado: (2017)

Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice
por: Hamm, Shelby E., et al.
Publicado: (2021)

Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice
por: Hamm, Shelby E., et al.
Publicado: (2021)

Bacterial Quorum-Sensing Molecules in Serum: A Potential Tool for Crohn's Disease Management
por: O'Connor, Gregory, et al.
Publicado: (2022)

Polyester dendrimers: a versatile nanocarrier for target specific drug delivery
por: Aravind, A, et al.
Publicado: (2012)

S2 Heart Sound Detects Aortic Valve Calcification Independent of Hemodynamic Changes in Mice
por: Dargam, Valentina, et al.
Publicado: (2022)

DNA Dendrimer: An Efficient Nanocarrier of Functional Nucleic Acids for Intracellular Molecular Sensing
por: Meng, Hong-Min, et al.
Publicado: (2014)

Dendrimer-decorated nanogels: Efficient nanocarriers for biodistribution in vivo and chemotherapy of ovarian carcinoma
por: Li, Xin, et al.
Publicado: (2021)

Methylene Blue Is a Nonspecific Protein–Protein Interaction Inhibitor with Potential for Repurposing as an Antiviral for COVID-19
por: Chuang, Sung-Ting, et al.
Publicado: (2022)

Red-Shifted Aequorin Variants Incorporating Non-Canonical Amino Acids: Applications in In Vivo Imaging
por: Grinstead, Kristen M., et al.
Publicado: (2016)

Discrete Event Simulation Model of Sudden Cardiac Death Predicts High Impact of Preventive Interventions
por: Andreev, Victor P., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_d94ulq0i1p3saqmfuau0eob4s5