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S100B Protein as a Therapeutic Target in Multiple Sclerosis: The S100B Inhibitor Arundic Acid Protects from Chronic Experimental Autoimmune Encephalomyelitis
S100B is an astrocytic protein behaving at high concentration as a damage-associated molecular pattern molecule. A direct correlation between the increased amount of S100B and inflammatory processes has been demonstrated, and in particular, the inhibitor of S100B activity pentamidine has been shown...
Autores principales: | Camponeschi, Chiara, De Carluccio, Maria, Amadio, Susanna, Clementi, Maria Elisabetta, Sampaolese, Beatrice, Volonté, Cinzia, Tredicine, Maria, Romano Spica, Vincenzo, Di Liddo, Rosa, Ria, Francesco, Michetti, Fabrizio, Di Sante, Gabriele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708367/ https://www.ncbi.nlm.nih.gov/pubmed/34948360 http://dx.doi.org/10.3390/ijms222413558 |
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