Cargando…

Nanoparticle-Based RNAi Therapeutics Targeting Cancer Stem Cells: Update and Prospective

Cancer stem cells (CSCs) are characterized by intrinsic self-renewal and tumorigenic properties, and play important roles in tumor initiation, progression, and resistance to diverse forms of anticancer therapy. Accordingly, targeting signaling pathways that are critical for CSC maintenance and biofu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Yongquan, Chen, Yan, Zhang, Zhe, Tang, Bo, Zhou, Zongguang, Chen, Haining
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708448/ https://www.ncbi.nlm.nih.gov/pubmed/34959397 http://dx.doi.org/10.3390/pharmaceutics13122116

Ejemplares similares

Nanoparticle-Based Delivery of RNAi Therapeutics: Progress and Challenges
por: Zhou, Jiehua, et al.
Publicado: (2013)

RNAi-based therapeutics–current status, challenges and prospects
por: Tiemann, Katrin, et al.
Publicado: (2009)

GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update
por: Gilsdorf, Moritz, et al.
Publicado: (2010)

Cationic liquid crystalline nanoparticles for the delivery of synthetic RNAi-based therapeutics
por: Gentile, Emanuela, et al.
Publicado: (2017)

A novel therapeutic strategy for cartilage diseases based on lipid nanoparticle-RNAi delivery system
por: Wang, Shaowei, et al.
Publicado: (2018)

Nanoparticle Delivery Platforms for RNAi Therapeutics Targeting COVID-19 Disease in the Respiratory Tract
por: Zhang, Yuan, et al.
Publicado: (2022)

GenomeRNAi: a database for cell-based and in vivo RNAi phenotypes, 2013 update
por: Schmidt, Esther E., et al.
Publicado: (2013)

Mucosal Delivery of RNAi Therapeutics
por: González, Borja Ballarín, et al.
Publicado: (2012)

Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas
por: Pang, Hao-Han, et al.
Publicado: (2023)

FlyRNAi.org—the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update
por: Hu, Yanhui, et al.
Publicado: (2017)

FlyRNAi.org—the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update
por: Hu, Yanhui, et al.
Publicado: (2020)

Targeting Caspase-3 as Dual Therapeutic Benefits by RNAi Facilitating Brain-Targeted Nanoparticles in a Rat Model of Parkinson’s Disease
por: Liu, Yang, et al.
Publicado: (2013)

FlyRNAi.org—the database of the Drosophila RNAi screening center: 2012 update
por: Flockhart, Ian T., et al.
Publicado: (2012)

From Intestinal Epithelial Homeostasis to Colorectal Cancer: Autophagy Regulation in Cellular Stress
por: Liu, Qiuluo, et al.
Publicado: (2022)

Correction: Targeting Caspase-3 as Dual Therapeutic Benefits by RNAi Facilitating Brain-Targeted Nanoparticles in a Rat Model of Parkinson’s Disease
por: Liu, Yang, et al.
Publicado: (2013)

A genome‐wide RNAi screen reveals essential therapeutic targets of breast cancer stem cells
por: Arfaoui, Abir, et al.
Publicado: (2019)

iRGD-Targeted Peptide Nanoparticles for Anti-Angiogenic RNAi-Based Therapy of Endometriosis
por: Egorova, Anna, et al.
Publicado: (2023)

Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics
por: Li, Ying Hong, et al.
Publicado: (2018)

The Business of RNAi Therapeutics in 2012
por: Haussecker, Dirk
Publicado: (2012)

RNAi Therapeutics in Autoimmune Disease
por: Pauley, Kaleb M., et al.
Publicado: (2013)

E-RNAi: a web application for the multi-species design of RNAi reagents—2010 update
por: Horn, Thomas, et al.
Publicado: (2010)

A RNAi-based therapeutic proof of concept targets salmonid whirling disease in vivo
por: Sarker, Subhodeep, et al.
Publicado: (2017)

RNAi-Based Therapeutics and Novel RNA Bioengineering Technologies
por: Traber, Gavin M., et al.
Publicado: (2023)

Targeting β-secretase with RNAi in neural stem cells for Alzheimer's disease therapy
por: Liu, Zhonghua, et al.
Publicado: (2013)

An investigational RNAi therapeutic targeting antithrombin for the treatment of hemophilia A and B
por: Machin, Nicoletta, et al.
Publicado: (2018)

Multimerized self-assembled caged two-in-one siRNA nanoparticles for photomodulation of RNAi-induced gene silencing
por: Chen, Changmai, et al.
Publicado: (2020)

Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information
por: Yang, Hong, et al.
Publicado: (2016)

A status report on RNAi therapeutics
por: Vaishnaw, Akshay K, et al.
Publicado: (2010)

RNAi Therapeutic Platforms for Lung Diseases
por: Fujita, Yu, et al.
Publicado: (2013)

Surgical treatment and prognosis of gastric neuroendocrine neoplasms: a single-center experience
por: Shen, Chaoyong, et al.
Publicado: (2016)

Opportunities and challenges in the nanoparticles for nucleic acid therapeutics: the first approval of an RNAi nanoparticle for treatment of a rare disease
por: Wei, Xiawei, et al.
Publicado: (2019)

Prospects for RNAi Therapy of COVID-19
por: Uludağ, Hasan, et al.
Publicado: (2020)

Insight Into the Prospects for RNAi Therapy of Cancer
por: Tian, Zhili, et al.
Publicado: (2021)

Application of mPEG-CS-cRGD/Bmi-1RNAi-PTX nanoparticles in suppression of laryngeal cancer by targeting cancer stem cells
por: Xu, Xiaoyan, et al.
Publicado: (2023)

Bacterial-mediated RNAi and functional analysis of Natalisin in a moth
por: Wang, Xia-Fei, et al.
Publicado: (2021)

Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration
por: Muralidharan, Ranganayaki, et al.
Publicado: (2016)

Triggering RNAi with multifunctional RNA nanoparticles and their delivery
por: Dao, Bich Ngoc, et al.
Publicado: (2015)

RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma
por: Arora, Shilpi, et al.
Publicado: (2010)

Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection
por: Wooddell, Christine I, et al.
Publicado: (2013)

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
por: Davis, Mark E., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_umjcmm78ji8j4n1gm26gq0r679