Cargando…

Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression

Recent years have witnessed major progress in development of novel therapeutic agents such as chemotherapy, targeted therapy and immune checkpoint inhibitors for breast cancer. However, cancer-related death remains high especially in triple-negative breast cancer (TNBC) due limited therapeutic optio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barnawi, Rayanah, Al-Khaldi, Samiyah, Majid, Salma, Qattan, Amal, Bakheet, Tala, Fallatah, Mohannad, Ghebeh, Hazem, Alajez, Nehad M., Al-Alwan, Monther
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708558/ https://www.ncbi.nlm.nih.gov/pubmed/34959629 http://dx.doi.org/10.3390/ph14121228

Ejemplares similares

Fascin Activates β-Catenin Signaling and Promotes Breast Cancer Stem Cell Function Mainly Through Focal Adhesion Kinase (FAK): Relation With Disease Progression
por: Barnawi, Rayanah, et al.
Publicado: (2020)

β1 Integrin is essential for fascin‐mediated breast cancer stem cell function and disease progression
por: Barnawi, Rayanah, et al.
Publicado: (2019)

Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway
por: Ghebeh, H, et al.
Publicado: (2014)

Fascin Is a Key Regulator of Breast Cancer Invasion That Acts via the Modification of Metastasis-Associated Molecules
por: Al-Alwan, Monther, et al.
Publicado: (2011)

PD‐L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation
por: Almozyan, Sheema, et al.
Publicado: (2017)

PD-L1 is overexpressed on breast cancer stem cells through notch3/mTOR axis
por: Mansour, Fatmah A., et al.
Publicado: (2020)

WT1 peptide analogue WT1-126Y enhances leukemia lysis
por: Alqudaihi, Ghofran, et al.
Publicado: (2014)

Gene expression data analysis identifies multiple deregulated pathways in patients with asthma
por: Alrashoudi, Reem H., et al.
Publicado: (2018)

Bidirectional crosstalk between PD-L1 expression and epithelial to mesenchymal transition: Significance in claudin-low breast cancer cells
por: Alsuliman, Abdullah, et al.
Publicado: (2015)

Higher PD-L1 Immunohistochemical Detection Signal in Frozen Compared to Matched Paraffin-Embedded Formalin-Fixed Tissues
por: Ghebeh, Hazem, et al.
Publicado: (2021)

Epigenetic regulation of triple negative breast cancer (TNBC) by TGF-β signaling
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2021)

Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule
por: Ghebeh, Hazem, et al.
Publicado: (2010)

Long non-coding RNA AC099850.4 correlates with advanced disease state and predicts worse prognosis in triple-negative breast cancer
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2023)

Computational and Transcriptome Analyses Revealed Preferential Induction of Chemotaxis and Lipid Synthesis by SARS-CoV-2
por: Shaath, Hibah, et al.
Publicado: (2020)

LncRNA-Based Classification of Triple Negative Breast Cancer Revealed Inherent Tumor Heterogeneity and Vulnerabilities
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2022)

Differential marker expression by cultures rich in mesenchymal stem cells
por: Wetzig, Andrew, et al.
Publicado: (2013)

Weekly Paclitaxel given concurrently with Durvalumab has a favorable safety profile in triple-negative metastatic breast cancer
por: Ghebeh, Hazem, et al.
Publicado: (2021)

Fascin in Gynecological Cancers: An Update of the Literature
por: Gupta, Ishita, et al.
Publicado: (2021)

Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition
por: Elango, Ramesh, et al.
Publicado: (2021)

Molecular Classification of Breast Cancer Utilizing Long Non-Coding RNA (lncRNA) Transcriptomes Identifies Novel Diagnostic lncRNA Panel for Triple-Negative Breast Cancer
por: Shaath, Hibah, et al.
Publicado: (2021)

Fascin‐1 as a novel diagnostic marker of triple‐negative breast cancer
por: Wang, Chao‐Qun, et al.
Publicado: (2016)

Downregulation of fascin induces collective cell migration in triple‑negative breast cancer
por: Yamamoto, Yumiko, et al.
Publicado: (2023)

The Fascination of statistics /
Publicado: (1986)

The fascination of groups
por: Budden, F J
Publicado: (1972)

Endocrinology Is Fascinating
por: Azizi, Fereidoun
Publicado: (2016)

Fascinations of Science
Publicado: (1875)

The Fascination of Opthalmology
por: Stockard, Cecil
Publicado: (1913)

Fascination of Serpents
por: Comstock, J.
Publicado: (1846)

Analyses on K-ras mutations and fascin expression in patients with cardia cancer
por: Wei, Li, et al.
Publicado: (2019)

Photography & fascination : essays /
por: Kozloff, Max
Publicado: (1979)

Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy
por: Shaath, Hibah, et al.
Publicado: (2021)

Integrated Transcriptome and Pathway Analyses Revealed Multiple Activated Pathways in Breast Cancer
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2019)

Arabidopsis 14-3-3 Proteins: Fascinating and Less Fascinating Aspects
por: Jaspert, Nina, et al.
Publicado: (2011)

Novel miRNA Targets and Therapies in the Triple-Negative Breast Cancer Microenvironment: An Emerging Hope for a Challenging Disease
por: Qattan, Amal
Publicado: (2020)

Large-Scale Analysis of Gene Expression Data Reveals a Novel Gene Expression Signature Associated with Colorectal Cancer Distant Recurrence
por: Alajez, Nehad M.
Publicado: (2016)

Significance of BMI1 and FSCN1 Expression in Colorectal Cancer
por: Alajez, Nehad M.
Publicado: (2016)

COVID-19: complexity of disease severity revealed by systemic and localized single cell immune atlas
por: Alajez, Nehad M.
Publicado: (2021)

Essential genes in thyroid cancers: focus on fascin
por: Samimi, Hilda, et al.
Publicado: (2013)

Those fascinating numbers
por: Koninck, Jean-Marie De, et al.
Publicado: (2009)

Un concept fascinant
por: Wess, Julius, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_chik2475icpn77u8rnlsvqagbb