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The Utility of Pharmacogenetics Testing in Psychiatric Populations
The implementation of pharmacogenetic tests including multiple gene variants has shown promising potential as a decision-making tool for optimizing psychopharmacological treatment regimens and reducing treatment costs. However, the varying clinical validity of gene variants included in pharmacogenet...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708570/ https://www.ncbi.nlm.nih.gov/pubmed/34945734 http://dx.doi.org/10.3390/jpm11121262 |
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author | Jürgens, Gesche |
author_facet | Jürgens, Gesche |
author_sort | Jürgens, Gesche |
collection | PubMed |
description | The implementation of pharmacogenetic tests including multiple gene variants has shown promising potential as a decision-making tool for optimizing psychopharmacological treatment regimens and reducing treatment costs. However, the varying clinical validity of gene variants included in pharmacogenetic test batteries, and inconsistencies in their translation into medical recommendations between commercially available pharmacogenetic tests, complicates their rational implementation. Thus, there is a need for well-designed, reproducible studies documenting the clinical significance of the various genetic variants. |
format | Online Article Text |
id | pubmed-8708570 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87085702021-12-25 The Utility of Pharmacogenetics Testing in Psychiatric Populations Jürgens, Gesche J Pers Med Editorial The implementation of pharmacogenetic tests including multiple gene variants has shown promising potential as a decision-making tool for optimizing psychopharmacological treatment regimens and reducing treatment costs. However, the varying clinical validity of gene variants included in pharmacogenetic test batteries, and inconsistencies in their translation into medical recommendations between commercially available pharmacogenetic tests, complicates their rational implementation. Thus, there is a need for well-designed, reproducible studies documenting the clinical significance of the various genetic variants. MDPI 2021-12-01 /pmc/articles/PMC8708570/ /pubmed/34945734 http://dx.doi.org/10.3390/jpm11121262 Text en © 2021 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Editorial Jürgens, Gesche The Utility of Pharmacogenetics Testing in Psychiatric Populations |
title | The Utility of Pharmacogenetics Testing in Psychiatric Populations |
title_full | The Utility of Pharmacogenetics Testing in Psychiatric Populations |
title_fullStr | The Utility of Pharmacogenetics Testing in Psychiatric Populations |
title_full_unstemmed | The Utility of Pharmacogenetics Testing in Psychiatric Populations |
title_short | The Utility of Pharmacogenetics Testing in Psychiatric Populations |
title_sort | utility of pharmacogenetics testing in psychiatric populations |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708570/ https://www.ncbi.nlm.nih.gov/pubmed/34945734 http://dx.doi.org/10.3390/jpm11121262 |
work_keys_str_mv | AT jurgensgesche theutilityofpharmacogeneticstestinginpsychiatricpopulations AT jurgensgesche utilityofpharmacogeneticstestinginpsychiatricpopulations |