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Synthesis, Structural Characterization, and In Vitro and In Silico Antifungal Evaluation of Azo-Azomethine Pyrazoles (PhN(2)(PhOH)CHN(C(3)N(2)(CH(3))(3))PhR, R = H or NO(2))
The azo-azomethine imines, R(1)-N=N-R(2)-CH=N-R(3), are a class of active pharmacological ligands that have been prominent antifungal, antibacterial, and antitumor agents. In this study, four new azo-azomethines, R(1) = Ph, R(2) = phenol, and R(3) = pyrazol-Ph-R’ (R = H or NO(2)), have been synthesi...
Autores principales: | Fernandez, Dorancelly, Restrepo-Acevedo, Andrés, Rocha-Roa, Cristian, Le Lagadec, Ronan, Abonia, Rodrigo, Zacchino, Susana A., Gómez Castaño, Jovanny A., Cuenú-Cabezas, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708670/ https://www.ncbi.nlm.nih.gov/pubmed/34946516 http://dx.doi.org/10.3390/molecules26247435 |
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