Purification of Porcine Circovirus Type 2 Using an Affinity Chromatography Based on a Neutralizing Monoclonal Antibody against Viral Capsid Protein

Porcine circovirus type 2 (PCV2) is a DNA virus without an envelope. The viral particle is icosahedral and has a diameter of approximately 17 nm. In order to obtain the purified virus, a broad-spectrum monoclonal antibody 3A5 against PCV2 was coupled to CNBr-activated Sepharose(TM) 4B, and an affini...

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Detalles Bibliográficos
Autores principales: Bian, Haiqiao, Yu, Chong, Wei, Yanwu, Feng, Li, Liu, Changming, Huang, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708674/
https://www.ncbi.nlm.nih.gov/pubmed/34959519
http://dx.doi.org/10.3390/pathogens10121564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708674/
https://www.ncbi.nlm.nih.gov/pubmed/34959519
http://dx.doi.org/10.3390/pathogens10121564

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