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Herbal Products Used in Menopause and for Gynecological Disorders

Herbal products are often used as an alternative to pharmacological therapy. Menopausal symptoms and gynecological disorders (such as premenstrual syndrome and dysmenorrhea) are the indications where pharmacological therapy may have serious adverse events, hence many women prefer to use herbal produ...

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Autores principales: Kenda, Maša, Glavač, Nina Kočevar, Nagy, Milan, Sollner Dolenc, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708702/
https://www.ncbi.nlm.nih.gov/pubmed/34946512
http://dx.doi.org/10.3390/molecules26247421
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author Kenda, Maša
Glavač, Nina Kočevar
Nagy, Milan
Sollner Dolenc, Marija
author_facet Kenda, Maša
Glavač, Nina Kočevar
Nagy, Milan
Sollner Dolenc, Marija
author_sort Kenda, Maša
collection PubMed
description Herbal products are often used as an alternative to pharmacological therapy. Menopausal symptoms and gynecological disorders (such as premenstrual syndrome and dysmenorrhea) are the indications where pharmacological therapy may have serious adverse events, hence many women prefer to use herbal products to help with these symptoms. Here, we reviewed plants and derived products, which are commonly used for the abovementioned indications, focusing on clinical data, safely profile and whether or not their use is justified. We noted that limited data are available on the use of some plants for alleviating the symptoms of menopause and gynecological disorders. While black cohosh (Cimicifuga racemose) and red clover (Trifolium pretense) were consistently shown to help reduce menopausal symptoms in clinical studies, currently available data do not fully support the use of fenugreek (Trigonella foenum-graecum), hops (Humulus lupulus), valerian (Valeriana officinalis), and soybean (Glycine max and Glycine soja) for this indication. For premenstrual syndrome and premenstrual dysphoric disorder, chaste tree (Vitex agnus-castus) shows effectiveness, but more clinical studies are needed to confirm such effect upon the use of evening primrose (Oenothera biennis).
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spelling pubmed-87087022021-12-25 Herbal Products Used in Menopause and for Gynecological Disorders Kenda, Maša Glavač, Nina Kočevar Nagy, Milan Sollner Dolenc, Marija Molecules Review Herbal products are often used as an alternative to pharmacological therapy. Menopausal symptoms and gynecological disorders (such as premenstrual syndrome and dysmenorrhea) are the indications where pharmacological therapy may have serious adverse events, hence many women prefer to use herbal products to help with these symptoms. Here, we reviewed plants and derived products, which are commonly used for the abovementioned indications, focusing on clinical data, safely profile and whether or not their use is justified. We noted that limited data are available on the use of some plants for alleviating the symptoms of menopause and gynecological disorders. While black cohosh (Cimicifuga racemose) and red clover (Trifolium pretense) were consistently shown to help reduce menopausal symptoms in clinical studies, currently available data do not fully support the use of fenugreek (Trigonella foenum-graecum), hops (Humulus lupulus), valerian (Valeriana officinalis), and soybean (Glycine max and Glycine soja) for this indication. For premenstrual syndrome and premenstrual dysphoric disorder, chaste tree (Vitex agnus-castus) shows effectiveness, but more clinical studies are needed to confirm such effect upon the use of evening primrose (Oenothera biennis). MDPI 2021-12-08 /pmc/articles/PMC8708702/ /pubmed/34946512 http://dx.doi.org/10.3390/molecules26247421 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kenda, Maša
Glavač, Nina Kočevar
Nagy, Milan
Sollner Dolenc, Marija
Herbal Products Used in Menopause and for Gynecological Disorders
title Herbal Products Used in Menopause and for Gynecological Disorders
title_full Herbal Products Used in Menopause and for Gynecological Disorders
title_fullStr Herbal Products Used in Menopause and for Gynecological Disorders
title_full_unstemmed Herbal Products Used in Menopause and for Gynecological Disorders
title_short Herbal Products Used in Menopause and for Gynecological Disorders
title_sort herbal products used in menopause and for gynecological disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708702/
https://www.ncbi.nlm.nih.gov/pubmed/34946512
http://dx.doi.org/10.3390/molecules26247421
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