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Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery

Background. The use and effectiveness of intraoperative cell salvage has been analyzed in many surgical specialties. Until now, no data exist evaluating the efficacy of intraoperative cell salvage in cerebral aneurysm surgery. Aim. To evaluate the efficacy and cost effectiveness of intraoperative ce...

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Autores principales: Behmanesh, Bedjan, Gessler, Florian, Adam, Elisabeth, Strouhal, Ulrich, Won, Sae-Yeon, Dubinski, Daniel, Seifert, Volker, Konczalla, Juergen, Senft, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708740/
https://www.ncbi.nlm.nih.gov/pubmed/34945029
http://dx.doi.org/10.3390/jcm10245734
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author Behmanesh, Bedjan
Gessler, Florian
Adam, Elisabeth
Strouhal, Ulrich
Won, Sae-Yeon
Dubinski, Daniel
Seifert, Volker
Konczalla, Juergen
Senft, Christian
author_facet Behmanesh, Bedjan
Gessler, Florian
Adam, Elisabeth
Strouhal, Ulrich
Won, Sae-Yeon
Dubinski, Daniel
Seifert, Volker
Konczalla, Juergen
Senft, Christian
author_sort Behmanesh, Bedjan
collection PubMed
description Background. The use and effectiveness of intraoperative cell salvage has been analyzed in many surgical specialties. Until now, no data exist evaluating the efficacy of intraoperative cell salvage in cerebral aneurysm surgery. Aim. To evaluate the efficacy and cost effectiveness of intraoperative cell salvage in cerebral aneurysm surgery. Methods. Data were collected retrospectively for all the patients who underwent cerebral aneurysm surgery at our institution between 2013 and 2019. Routinely, we apply blood salvage through autotransfusion. The cases were divided into a ruptured cerebral aneurysm group and a unruptured cerebral aneurysm group. Results. A total of 241 patients underwent cerebral aneurysm clipping. Of all the cerebral aneurysms, 116 were ruptured and 125 were unruptured and clipped electively. Age, location of the aneurysm, postoperative red blood cell count, intraoperative blood loss, and number of allogenic blood cell transfusions were statistically significantly different between the groups. The autotransfusion of salvaged blood could only be facilitated in eight cases with ruptured cerebral aneurysms and in none with unruptured cerebral aneurysms clipped electively (p < 0.01). Additionally, 35 patients with ruptured cerebral aneurysms and one patient with unruptured cerebral aneurysm required allogenic red blood cell transfusion after surgery, and 71 vs. 2 units of blood were transfused (p < 0.0001). In terms of cost effectiveness, a total of EUR 45,189 in 241 patients was spent to run the autotransfusion system, while EUR 13,797 was spent for allogenic blood transfusion. Conclusions. The use of cell salvage in patients with unruptured cerebral aneurysm, undergoing elective surgery, is not effective.
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spelling pubmed-87087402021-12-25 Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery Behmanesh, Bedjan Gessler, Florian Adam, Elisabeth Strouhal, Ulrich Won, Sae-Yeon Dubinski, Daniel Seifert, Volker Konczalla, Juergen Senft, Christian J Clin Med Article Background. The use and effectiveness of intraoperative cell salvage has been analyzed in many surgical specialties. Until now, no data exist evaluating the efficacy of intraoperative cell salvage in cerebral aneurysm surgery. Aim. To evaluate the efficacy and cost effectiveness of intraoperative cell salvage in cerebral aneurysm surgery. Methods. Data were collected retrospectively for all the patients who underwent cerebral aneurysm surgery at our institution between 2013 and 2019. Routinely, we apply blood salvage through autotransfusion. The cases were divided into a ruptured cerebral aneurysm group and a unruptured cerebral aneurysm group. Results. A total of 241 patients underwent cerebral aneurysm clipping. Of all the cerebral aneurysms, 116 were ruptured and 125 were unruptured and clipped electively. Age, location of the aneurysm, postoperative red blood cell count, intraoperative blood loss, and number of allogenic blood cell transfusions were statistically significantly different between the groups. The autotransfusion of salvaged blood could only be facilitated in eight cases with ruptured cerebral aneurysms and in none with unruptured cerebral aneurysms clipped electively (p < 0.01). Additionally, 35 patients with ruptured cerebral aneurysms and one patient with unruptured cerebral aneurysm required allogenic red blood cell transfusion after surgery, and 71 vs. 2 units of blood were transfused (p < 0.0001). In terms of cost effectiveness, a total of EUR 45,189 in 241 patients was spent to run the autotransfusion system, while EUR 13,797 was spent for allogenic blood transfusion. Conclusions. The use of cell salvage in patients with unruptured cerebral aneurysm, undergoing elective surgery, is not effective. MDPI 2021-12-07 /pmc/articles/PMC8708740/ /pubmed/34945029 http://dx.doi.org/10.3390/jcm10245734 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Behmanesh, Bedjan
Gessler, Florian
Adam, Elisabeth
Strouhal, Ulrich
Won, Sae-Yeon
Dubinski, Daniel
Seifert, Volker
Konczalla, Juergen
Senft, Christian
Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery
title Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery
title_full Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery
title_fullStr Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery
title_full_unstemmed Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery
title_short Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery
title_sort efficacy of intraoperative blood salvage in cerebral aneurysm surgery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708740/
https://www.ncbi.nlm.nih.gov/pubmed/34945029
http://dx.doi.org/10.3390/jcm10245734
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