Improved Peripheral and Hepatic Insulin Sensitivity after Lifestyle Interventions in Type 2 Diabetes Is Associated with Specific Metabolomic and Lipidomic Signatures in Skeletal Muscle and Plasma

Lifestyle interventions with weight loss can improve insulin sensitivity in type 2 diabetes (T2D), but mechanisms are unclear. We explored circulating and skeletal muscle metabolite signatures of altered peripheral (pIS) and hepatic insulin sensitivity (hIS) in overweight and obese T2D individuals t...

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Detalles Bibliográficos
Autores principales: Chorell, Elin, Otten, Julia, Stomby, Andreas, Ryberg, Mats, Waling, Maria, Hauksson, Jon, Svensson, Michael, Olsson, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708788/
https://www.ncbi.nlm.nih.gov/pubmed/34940592
http://dx.doi.org/10.3390/metabo11120834

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