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Improved Peripheral and Hepatic Insulin Sensitivity after Lifestyle Interventions in Type 2 Diabetes Is Associated with Specific Metabolomic and Lipidomic Signatures in Skeletal Muscle and Plasma
Lifestyle interventions with weight loss can improve insulin sensitivity in type 2 diabetes (T2D), but mechanisms are unclear. We explored circulating and skeletal muscle metabolite signatures of altered peripheral (pIS) and hepatic insulin sensitivity (hIS) in overweight and obese T2D individuals t...
Autores principales: | Chorell, Elin, Otten, Julia, Stomby, Andreas, Ryberg, Mats, Waling, Maria, Hauksson, Jon, Svensson, Michael, Olsson, Tommy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708788/ https://www.ncbi.nlm.nih.gov/pubmed/34940592 http://dx.doi.org/10.3390/metabo11120834 |
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