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Discovery of a Novel Template, 7-Substituted 7-Deaza-4′-Thioadenosine Derivatives as Multi-Kinase Inhibitors

The development of anticancer drugs remains challenging owing to the potential for drug resistance. The simultaneous inhibition of multiple targets involved in cancer could overcome resistance, and these agents would exhibit higher potency than single-target inhibitors. Protein kinases represent a p...

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Detalles Bibliográficos
Autores principales:	Mashelkar, Karishma K., Byun, Woong Sub, Ko, Hyejin, Sung, Kisu, Tripathi, Sushil K., An, Seungchan, Yum, Yun A, Kwon, Jee Youn, Kim, Minjae, Kim, Gibae, Kwon, Eun-Ji, Lee, Hyuk Woo, Noh, Minsoo, Lee, Sang Kook, Jeong, Lak Shin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708872/ https://www.ncbi.nlm.nih.gov/pubmed/34959689 http://dx.doi.org/10.3390/ph14121290

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