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Revisiting One-Stage Urethroplasties for Distal Urethral Strictures

Background: Reconstructive approaches for distal urethral strictures range from simple meatotomy to utilizing grafts or flaps depending on the etiology, length and location. We describe a contemporary cohort of distal urethral strictures and report a surgical technique termed distal one-stage urethr...

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Autores principales: Hofer, Matthias D., Cooley, Lauren Folgosa, Elmasri, Ayman, Martins, Francisco E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708882/
https://www.ncbi.nlm.nih.gov/pubmed/34945200
http://dx.doi.org/10.3390/jcm10245905
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author Hofer, Matthias D.
Cooley, Lauren Folgosa
Elmasri, Ayman
Martins, Francisco E.
author_facet Hofer, Matthias D.
Cooley, Lauren Folgosa
Elmasri, Ayman
Martins, Francisco E.
author_sort Hofer, Matthias D.
collection PubMed
description Background: Reconstructive approaches for distal urethral strictures range from simple meatotomy to utilizing grafts or flaps depending on the etiology, length and location. We describe a contemporary cohort of distal urethral strictures and report a surgical technique termed distal one-stage urethroplasty developed to address the majority of distal urethral strictures encountered. Methods: Thirty-four patients were included. The mean age was 56.7 years (range 15.7–84.9 years), the mean stricture length was 1.1 cm (0.5–1.5) and the mean follow-up was 42.5 months (28–61.3). Results: The vast majority of distal strictures (27/34 (79.4%)) were treated with our hybrid one-stage approach combining a distal urethral reconstruction with excision of the scar tissue without the need to use grafts or flaps. The average stricture length was 0.68 cm and average operative time was 24.43 min. Post-operative spraying was reported in a minority of patients (4/27 (14.8%)). The length of stricture and surgery were significantly longer in those 7/34 (20.6%) patients in whom grafts or flaps were used (2.88 cm and 154.8 min, respectively, p < 0.001 for both when compared to the hybrid one-stage approach). We noted 6/34 (17.6%) recurrences of distal urethral strictures, all of which were treated successfully with graft and flap repairs. Conclusions: The vast majority of distal urethral strictures are amenable to a distal one-stage urethroplasty, avoiding the use of grafts and/or flaps while achieving reasonable outcomes. This limited approach, at least initially, is associated with shorter operative time and time of catheter placement and avoids morbidity associated with graft or flap harvesting. Spraying of urine is seldomly encountered and comparable to other approaches addressing distal urethral strictures.
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spelling pubmed-87088822021-12-25 Revisiting One-Stage Urethroplasties for Distal Urethral Strictures Hofer, Matthias D. Cooley, Lauren Folgosa Elmasri, Ayman Martins, Francisco E. J Clin Med Article Background: Reconstructive approaches for distal urethral strictures range from simple meatotomy to utilizing grafts or flaps depending on the etiology, length and location. We describe a contemporary cohort of distal urethral strictures and report a surgical technique termed distal one-stage urethroplasty developed to address the majority of distal urethral strictures encountered. Methods: Thirty-four patients were included. The mean age was 56.7 years (range 15.7–84.9 years), the mean stricture length was 1.1 cm (0.5–1.5) and the mean follow-up was 42.5 months (28–61.3). Results: The vast majority of distal strictures (27/34 (79.4%)) were treated with our hybrid one-stage approach combining a distal urethral reconstruction with excision of the scar tissue without the need to use grafts or flaps. The average stricture length was 0.68 cm and average operative time was 24.43 min. Post-operative spraying was reported in a minority of patients (4/27 (14.8%)). The length of stricture and surgery were significantly longer in those 7/34 (20.6%) patients in whom grafts or flaps were used (2.88 cm and 154.8 min, respectively, p < 0.001 for both when compared to the hybrid one-stage approach). We noted 6/34 (17.6%) recurrences of distal urethral strictures, all of which were treated successfully with graft and flap repairs. Conclusions: The vast majority of distal urethral strictures are amenable to a distal one-stage urethroplasty, avoiding the use of grafts and/or flaps while achieving reasonable outcomes. This limited approach, at least initially, is associated with shorter operative time and time of catheter placement and avoids morbidity associated with graft or flap harvesting. Spraying of urine is seldomly encountered and comparable to other approaches addressing distal urethral strictures. MDPI 2021-12-16 /pmc/articles/PMC8708882/ /pubmed/34945200 http://dx.doi.org/10.3390/jcm10245905 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hofer, Matthias D.
Cooley, Lauren Folgosa
Elmasri, Ayman
Martins, Francisco E.
Revisiting One-Stage Urethroplasties for Distal Urethral Strictures
title Revisiting One-Stage Urethroplasties for Distal Urethral Strictures
title_full Revisiting One-Stage Urethroplasties for Distal Urethral Strictures
title_fullStr Revisiting One-Stage Urethroplasties for Distal Urethral Strictures
title_full_unstemmed Revisiting One-Stage Urethroplasties for Distal Urethral Strictures
title_short Revisiting One-Stage Urethroplasties for Distal Urethral Strictures
title_sort revisiting one-stage urethroplasties for distal urethral strictures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708882/
https://www.ncbi.nlm.nih.gov/pubmed/34945200
http://dx.doi.org/10.3390/jcm10245905
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