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Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis

Background: Current evidence points to a state of hypercoagulability (consequence of hyperinflammation) as an important pathogenic mechanism that contributes to the increase in mortality in cases of COVID-19. The aim of the present study was to investigate the influence of deep-vein thrombosis on mo...

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Autores principales: Pereira de Godoy, Jose Maria, Russeff, Gleison Juliano da Silva, Costa, Carolina Hungaro, Sato, Debora Yuri, Silva, Desirée Franccini Del Frari, Guerreiro Godoy, Maria de Fatima, Pereira de Godoy, Henrique Jose, Espada, Paulo César
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708913/
https://www.ncbi.nlm.nih.gov/pubmed/34940287
http://dx.doi.org/10.3390/medicines8120075
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author Pereira de Godoy, Jose Maria
Russeff, Gleison Juliano da Silva
Costa, Carolina Hungaro
Sato, Debora Yuri
Silva, Desirée Franccini Del Frari
Guerreiro Godoy, Maria de Fatima
Pereira de Godoy, Henrique Jose
Espada, Paulo César
author_facet Pereira de Godoy, Jose Maria
Russeff, Gleison Juliano da Silva
Costa, Carolina Hungaro
Sato, Debora Yuri
Silva, Desirée Franccini Del Frari
Guerreiro Godoy, Maria de Fatima
Pereira de Godoy, Henrique Jose
Espada, Paulo César
author_sort Pereira de Godoy, Jose Maria
collection PubMed
description Background: Current evidence points to a state of hypercoagulability (consequence of hyperinflammation) as an important pathogenic mechanism that contributes to the increase in mortality in cases of COVID-19. The aim of the present study was to investigate the influence of deep-vein thrombosis on mortality patient’s infected with SARS-CoV-2. Method: A clinical trial was conducted involving 200 consecutive patients with COVID-19—100 patients who were positive for deep-vein thrombosis (venous Doppler ultrasound) and 100 who were negative for deep-vein thrombosis at a public hospital. Results: The mortality rate was 67% in the group positive for DVT and 31% in the group negative for DVT. Conclusion: Deep-vein thrombosis is associated with an increase in mortality in patients with COVID-19 and failures can occur with conventional prophylaxis for deep-vein thrombosis.
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spelling pubmed-87089132021-12-25 Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis Pereira de Godoy, Jose Maria Russeff, Gleison Juliano da Silva Costa, Carolina Hungaro Sato, Debora Yuri Silva, Desirée Franccini Del Frari Guerreiro Godoy, Maria de Fatima Pereira de Godoy, Henrique Jose Espada, Paulo César Medicines (Basel) Article Background: Current evidence points to a state of hypercoagulability (consequence of hyperinflammation) as an important pathogenic mechanism that contributes to the increase in mortality in cases of COVID-19. The aim of the present study was to investigate the influence of deep-vein thrombosis on mortality patient’s infected with SARS-CoV-2. Method: A clinical trial was conducted involving 200 consecutive patients with COVID-19—100 patients who were positive for deep-vein thrombosis (venous Doppler ultrasound) and 100 who were negative for deep-vein thrombosis at a public hospital. Results: The mortality rate was 67% in the group positive for DVT and 31% in the group negative for DVT. Conclusion: Deep-vein thrombosis is associated with an increase in mortality in patients with COVID-19 and failures can occur with conventional prophylaxis for deep-vein thrombosis. MDPI 2021-11-29 /pmc/articles/PMC8708913/ /pubmed/34940287 http://dx.doi.org/10.3390/medicines8120075 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pereira de Godoy, Jose Maria
Russeff, Gleison Juliano da Silva
Costa, Carolina Hungaro
Sato, Debora Yuri
Silva, Desirée Franccini Del Frari
Guerreiro Godoy, Maria de Fatima
Pereira de Godoy, Henrique Jose
Espada, Paulo César
Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title_full Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title_fullStr Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title_full_unstemmed Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title_short Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title_sort mortality of patients infected by covid-19 with and without deep-vein thrombosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708913/
https://www.ncbi.nlm.nih.gov/pubmed/34940287
http://dx.doi.org/10.3390/medicines8120075
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