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Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
Background: Current evidence points to a state of hypercoagulability (consequence of hyperinflammation) as an important pathogenic mechanism that contributes to the increase in mortality in cases of COVID-19. The aim of the present study was to investigate the influence of deep-vein thrombosis on mo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708913/ https://www.ncbi.nlm.nih.gov/pubmed/34940287 http://dx.doi.org/10.3390/medicines8120075 |
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author | Pereira de Godoy, Jose Maria Russeff, Gleison Juliano da Silva Costa, Carolina Hungaro Sato, Debora Yuri Silva, Desirée Franccini Del Frari Guerreiro Godoy, Maria de Fatima Pereira de Godoy, Henrique Jose Espada, Paulo César |
author_facet | Pereira de Godoy, Jose Maria Russeff, Gleison Juliano da Silva Costa, Carolina Hungaro Sato, Debora Yuri Silva, Desirée Franccini Del Frari Guerreiro Godoy, Maria de Fatima Pereira de Godoy, Henrique Jose Espada, Paulo César |
author_sort | Pereira de Godoy, Jose Maria |
collection | PubMed |
description | Background: Current evidence points to a state of hypercoagulability (consequence of hyperinflammation) as an important pathogenic mechanism that contributes to the increase in mortality in cases of COVID-19. The aim of the present study was to investigate the influence of deep-vein thrombosis on mortality patient’s infected with SARS-CoV-2. Method: A clinical trial was conducted involving 200 consecutive patients with COVID-19—100 patients who were positive for deep-vein thrombosis (venous Doppler ultrasound) and 100 who were negative for deep-vein thrombosis at a public hospital. Results: The mortality rate was 67% in the group positive for DVT and 31% in the group negative for DVT. Conclusion: Deep-vein thrombosis is associated with an increase in mortality in patients with COVID-19 and failures can occur with conventional prophylaxis for deep-vein thrombosis. |
format | Online Article Text |
id | pubmed-8708913 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87089132021-12-25 Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis Pereira de Godoy, Jose Maria Russeff, Gleison Juliano da Silva Costa, Carolina Hungaro Sato, Debora Yuri Silva, Desirée Franccini Del Frari Guerreiro Godoy, Maria de Fatima Pereira de Godoy, Henrique Jose Espada, Paulo César Medicines (Basel) Article Background: Current evidence points to a state of hypercoagulability (consequence of hyperinflammation) as an important pathogenic mechanism that contributes to the increase in mortality in cases of COVID-19. The aim of the present study was to investigate the influence of deep-vein thrombosis on mortality patient’s infected with SARS-CoV-2. Method: A clinical trial was conducted involving 200 consecutive patients with COVID-19—100 patients who were positive for deep-vein thrombosis (venous Doppler ultrasound) and 100 who were negative for deep-vein thrombosis at a public hospital. Results: The mortality rate was 67% in the group positive for DVT and 31% in the group negative for DVT. Conclusion: Deep-vein thrombosis is associated with an increase in mortality in patients with COVID-19 and failures can occur with conventional prophylaxis for deep-vein thrombosis. MDPI 2021-11-29 /pmc/articles/PMC8708913/ /pubmed/34940287 http://dx.doi.org/10.3390/medicines8120075 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pereira de Godoy, Jose Maria Russeff, Gleison Juliano da Silva Costa, Carolina Hungaro Sato, Debora Yuri Silva, Desirée Franccini Del Frari Guerreiro Godoy, Maria de Fatima Pereira de Godoy, Henrique Jose Espada, Paulo César Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis |
title | Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis |
title_full | Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis |
title_fullStr | Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis |
title_full_unstemmed | Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis |
title_short | Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis |
title_sort | mortality of patients infected by covid-19 with and without deep-vein thrombosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708913/ https://www.ncbi.nlm.nih.gov/pubmed/34940287 http://dx.doi.org/10.3390/medicines8120075 |
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