Transient Activation of Hedgehog Signaling Inhibits Cellular Senescence and Inflammation in Radiated Swine Salivary Glands through Preserving Resident Macrophages

Salivary gland function is commonly and irreversibly damaged by radiation therapy for head and neck cancer. This damage greatly decreases the patient’s quality of life and is difficult to remedy. Previously, we found that the transient activation of Hedgehog signaling alleviated salivary hypofunctio...

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Detalles Bibliográficos
Autores principales: Hu, Liang, Du, Conglin, Yang, Zi, Yang, Yang, Zhu, Zhao, Shan, Zhaochen, Zhang, Chunmei, Wang, Songlin, Liu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8708934/
https://www.ncbi.nlm.nih.gov/pubmed/34948290
http://dx.doi.org/10.3390/ijms222413493

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