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An Effective and Robust Approach Based on R-CNN+LSTM Model and NCAR Feature Selection for Ophthalmological Disease Detection from Fundus Images

Changes in and around anatomical structures such as blood vessels, optic disc, fovea, and macula can lead to ophthalmological diseases such as diabetic retinopathy, glaucoma, age-related macular degeneration (AMD), myopia, hypertension, and cataracts. If these diseases are not diagnosed early, they...

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Detalles Bibliográficos
Autores principales: Demir, Fatih, Taşcı, Burak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709012/
https://www.ncbi.nlm.nih.gov/pubmed/34945747
http://dx.doi.org/10.3390/jpm11121276
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author Demir, Fatih
Taşcı, Burak
author_facet Demir, Fatih
Taşcı, Burak
author_sort Demir, Fatih
collection PubMed
description Changes in and around anatomical structures such as blood vessels, optic disc, fovea, and macula can lead to ophthalmological diseases such as diabetic retinopathy, glaucoma, age-related macular degeneration (AMD), myopia, hypertension, and cataracts. If these diseases are not diagnosed early, they may cause partial or complete loss of vision in patients. Fundus imaging is the primary method used to diagnose ophthalmologic diseases. In this study, a powerful R-CNN+LSTM-based approach is proposed that automatically detects eight different ophthalmologic diseases from fundus images. Deep features were extracted from fundus images with the proposed R-CNN+LSTM structure. Among the deep features extracted, those with high representative power were selected with an approach called NCAR, which is a multilevel feature selection algorithm. In the classification phase, the SVM algorithm, which is a powerful classifier, was used. The proposed approach is evaluated on the eight-class ODIR dataset. The accuracy (main metric), sensitivity, specificity, and precision metrics were used for the performance evaluation of the proposed approach. Besides, the performance of the proposed approach was compared with the existing approaches using the ODIR dataset.
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spelling pubmed-87090122021-12-25 An Effective and Robust Approach Based on R-CNN+LSTM Model and NCAR Feature Selection for Ophthalmological Disease Detection from Fundus Images Demir, Fatih Taşcı, Burak J Pers Med Article Changes in and around anatomical structures such as blood vessels, optic disc, fovea, and macula can lead to ophthalmological diseases such as diabetic retinopathy, glaucoma, age-related macular degeneration (AMD), myopia, hypertension, and cataracts. If these diseases are not diagnosed early, they may cause partial or complete loss of vision in patients. Fundus imaging is the primary method used to diagnose ophthalmologic diseases. In this study, a powerful R-CNN+LSTM-based approach is proposed that automatically detects eight different ophthalmologic diseases from fundus images. Deep features were extracted from fundus images with the proposed R-CNN+LSTM structure. Among the deep features extracted, those with high representative power were selected with an approach called NCAR, which is a multilevel feature selection algorithm. In the classification phase, the SVM algorithm, which is a powerful classifier, was used. The proposed approach is evaluated on the eight-class ODIR dataset. The accuracy (main metric), sensitivity, specificity, and precision metrics were used for the performance evaluation of the proposed approach. Besides, the performance of the proposed approach was compared with the existing approaches using the ODIR dataset. MDPI 2021-12-02 /pmc/articles/PMC8709012/ /pubmed/34945747 http://dx.doi.org/10.3390/jpm11121276 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Demir, Fatih
Taşcı, Burak
An Effective and Robust Approach Based on R-CNN+LSTM Model and NCAR Feature Selection for Ophthalmological Disease Detection from Fundus Images
title An Effective and Robust Approach Based on R-CNN+LSTM Model and NCAR Feature Selection for Ophthalmological Disease Detection from Fundus Images
title_full An Effective and Robust Approach Based on R-CNN+LSTM Model and NCAR Feature Selection for Ophthalmological Disease Detection from Fundus Images
title_fullStr An Effective and Robust Approach Based on R-CNN+LSTM Model and NCAR Feature Selection for Ophthalmological Disease Detection from Fundus Images
title_full_unstemmed An Effective and Robust Approach Based on R-CNN+LSTM Model and NCAR Feature Selection for Ophthalmological Disease Detection from Fundus Images
title_short An Effective and Robust Approach Based on R-CNN+LSTM Model and NCAR Feature Selection for Ophthalmological Disease Detection from Fundus Images
title_sort effective and robust approach based on r-cnn+lstm model and ncar feature selection for ophthalmological disease detection from fundus images
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709012/
https://www.ncbi.nlm.nih.gov/pubmed/34945747
http://dx.doi.org/10.3390/jpm11121276
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