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Transcriptome-Wide Analysis of Human Liver Reveals Age-Related Differences in the Expression of Select Functional Gene Clusters and Evidence for a PPP1R10-Governed ‘Aging Cascade’

A transcriptome-wide analysis of human liver for demonstrating differences between young and old humans has not yet been performed. However, identifying major age-related alterations in hepatic gene expression may pinpoint ontogenetic shifts with important hepatic and systemic consequences, provide...

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Detalles Bibliográficos
Autores principales: Schreiter, Thomas, Gieseler, Robert K., Vílchez-Vargas, Ramiro, Jauregui, Ruy, Sowa, Jan-Peter, Klein-Scory, Susanne, Broering, Ruth, Croner, Roland S., Treckmann, Jürgen W., Link, Alexander, Canbay, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709089/
https://www.ncbi.nlm.nih.gov/pubmed/34959291
http://dx.doi.org/10.3390/pharmaceutics13122009