Safety, Immunogenicity, and Protective Efficacy of an H5N1 Chimeric Cold-Adapted Attenuated Virus Vaccine in a Mouse Model

H5N1 influenza virus is a threat to public health worldwide. The virus can cause severe morbidity and mortality in humans. We constructed an H5N1 influenza candidate virus vaccine from the A/chicken/Guizhou/1153/2016 strain that was recommended by the World Health Organization. In this study, we des...

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Detalles Bibliográficos
Autores principales: Sun, Weiyang, Wang, Zhenfei, Sun, Yue, Li, Dongxu, Zhu, Menghan, Zhao, Menglin, Wang, Yutian, Xu, Jiaqi, Kong, Yunyi, Li, Yuanguo, Feng, Na, Wang, Tiecheng, Zhao, Yongkun, Yang, Songtao, Gao, Yuwei, Xia, Xianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709164/
https://www.ncbi.nlm.nih.gov/pubmed/34960689
http://dx.doi.org/10.3390/v13122420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709164/
https://www.ncbi.nlm.nih.gov/pubmed/34960689
http://dx.doi.org/10.3390/v13122420

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