Cargando…
Safety, Immunogenicity, and Protective Efficacy of an H5N1 Chimeric Cold-Adapted Attenuated Virus Vaccine in a Mouse Model
H5N1 influenza virus is a threat to public health worldwide. The virus can cause severe morbidity and mortality in humans. We constructed an H5N1 influenza candidate virus vaccine from the A/chicken/Guizhou/1153/2016 strain that was recommended by the World Health Organization. In this study, we des...
Autores principales: | Sun, Weiyang, Wang, Zhenfei, Sun, Yue, Li, Dongxu, Zhu, Menghan, Zhao, Menglin, Wang, Yutian, Xu, Jiaqi, Kong, Yunyi, Li, Yuanguo, Feng, Na, Wang, Tiecheng, Zhao, Yongkun, Yang, Songtao, Gao, Yuwei, Xia, Xianzhu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709164/ https://www.ncbi.nlm.nih.gov/pubmed/34960689 http://dx.doi.org/10.3390/v13122420 |
Ejemplares similares
-
Amino acid sites related to the PB2 subunits of IDV affect polymerase activity
por: Wang, Yutian, et al.
Publicado: (2021) -
Cross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammals
por: Sun, Weiyang, et al.
Publicado: (2023) -
PB1 S524G mutation of wild bird-origin H3N8 influenza A virus enhances virulence and fitness for transmission in mammals
por: Zhang, Xinghai, et al.
Publicado: (2021) -
Characteristics of Chimeric West Nile Virus Based on the Japanese Encephalitis Virus SA14-14-2 Backbone
por: Li, Guohua, et al.
Publicado: (2021) -
Identification and Characterization of Porcine Kobuvirus Variant Isolated from Suckling Piglet in Gansu Province, China
por: Fan, Shengtao, et al.
Publicado: (2013)