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Design and Synthesis of Hybrid Compounds as Epigenetic Modifiers

Epigenetic modifiers acting through polypharmacology mechanisms are promising compounds with which to treat several infectious diseases. Histone deacetylase (HDAC) enzymes, mainly class I, and extra-terminal bromodomains (BET) are involved in viral replication and the host response. In the present s...

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Detalles Bibliográficos
Autores principales:	Lopes, Juliana Romano, Prokopczyk, Igor Muccilo, Gerlack, Max, Man Chin, Chung, Santos, Jean Leandro Dos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709175/ https://www.ncbi.nlm.nih.gov/pubmed/34959707 http://dx.doi.org/10.3390/ph14121308

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